Journal of anesthesia
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Journal of anesthesia · Apr 2023
Review Meta AnalysisIntravenous oxytocin regimens in patients undergoing cesarean delivery: a systematic review and network meta-analysis of cluster-based groups.
Information on evaluations of different oxytocin regimens used to prevent post-partum hemorrhage during cesarean delivery is scarce, and there is a lack of statistically pooled results for comparative doses. In this review, we aimed to analyze the effectiveness of different oxytocin regimens used and rank them accordingly. We performed a meta-analysis of randomized controlled trials (RCTs) reporting the incidence of additional uterotonic (AUT) use or amount of blood loss during cesarean delivery, where different oxytocin regimens were compared. ⋯ In contrast, the dose range, > 5 IU regimen was associated with higher side effects (lowest rank). During cesarean delivery, a significant reduction in the use of AUTs or blood loss (Rank 2) was recorded for bolus-infusion combination regimens. High doses did not have enough evidence to draw meaningful conclusions.
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Journal of anesthesia · Apr 2023
Case ReportsMotor-evoked potentials monitoring with remimazolam during thoracic descending aortic aneurysm surgery: a case report.
Paraplegia remains the most devastating complication following thoracoabdominal aortic surgery. Motor-evoked potential (MEP) monitoring has been widely used to assess intraoperative motor function. MEP amplitude is affected by various factors, including anesthetic agents and measurement time; however, there are no reports regarding MEP monitoring using remimazolam in thoracoabdominal aortic surgery. ⋯ There were no significant changes, which were defined as a 50% reduction of MEP amplitude from each baseline value, including during split circulation. On postoperative day one, she had no motor deficits nor signs of intraoperative awareness. Remimazolam might be well tolerated for MEP monitoring in patients undergoing thoracic descending aortic aneurysm surgery.