Journal of anesthesia
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Journal of anesthesia · Jan 2002
Effects of fentanyl on cardiovascular and plasma catecholamine responses in surgical patients.
Whether opioids administered before skin incision, under inhalational anesthesia, improve cardiovascular and plasma catecholamine responses to surgical stimulation compared with those administered after skin incision remains unclear. We compared the effects of fentanyl injected before and after skin incision on these responses. ⋯ Our results indicated that fentanyl depressed cardiovascular and plasma catecholamine responses irrespective of the time of administration, and that the higher dose of fentanyl produced a greater suppression of MAP and HR responses. In addition, the depressant effects on MAP of high-dose fentanyl administered 5 min before skin incision lasted longer than when injected 5 min after incision. At both doses, the opioid attenuated the rise in plasma Epi, but not Nor.
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Journal of anesthesia · Jan 2002
Randomized Controlled Trial Clinical TrialComparison of heart rate changes after neostigmine-atropine administration during recovery from propofol-N2O and isoflurane-N2O anesthesia.
Propofol augments the reduction of heart rate (HR) in combination with cholinergic agents and attenuates the HR response to atropine. We examined whether propofol anesthesia was associated with an increased incidence and extent of bradycardia after neostigmine-atropine administration compared with the effects of isoflurane anesthesia. ⋯ We conclude that propofol anesthesia attenuates the initial increases in HR, enhances the subsequent decreases in HR, and increases the incidence of bradycardia after neostigmine-atropine injections compared with the effects of isoflurane anesthesia.
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Journal of anesthesia · Jan 2002
Randomized Controlled Trial Clinical TrialComparative effect of 6% hydroxyethyl starch (containing 1% dextrose) and lactated Ringer's solution for cesarean section under spinal anesthesia.
This study aimed to compare low-molecular weight hydroxyethyl starch containing 1% dextrose (HES) infusion and lactated Ringer's solution (LR) in the prevention of hypotension associated with spinal anesthesia for cesarean section. ⋯ This study did not show an advantage of HES compared with LR in the prevention of hypotension or in the reduction of ephedrine dose during cesarean section under spinal anesthesia. The anesthesia level, rather than the choice of intravenous fluid solution, might be related to the ephedrine dose.
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Journal of anesthesia · Jan 2002
Onset of vecuronium-induced neuromuscular block after a long priming interval.
We examined whether a new application of the priming principle, i.e., having the priming dose of vecuronium administered before the insertion of the epidural catheter, would hasten the onset of the neuromuscular block induced by the intubating dose of vecuronium. ⋯ If the priming dose of vecuronium is given after a long priming interval (16 +/- 3 min), the time to onset of the neuromuscular block caused by the intubating dose of vecuronium is markedly shorter than when the conventional priming interval of 4 min is employed.
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Journal of anesthesia · Jan 2002
Randomized Controlled Trial Clinical TrialThe effect of propofol infusion on minimum alveolar concentration of sevoflurane for smooth tracheal intubation.
This study was conducted to determine the effect of propofol infusion on the minimum alveolar concentration necessary for smooth tracheal intubation (MACEI) of sevoflurane. ⋯ Propofol infusion reduced sevoflurane MACEI. This finding suggests that propofol would be an excellent adjuvant to use with sevoflurane for tracheal intubation.