Journal of anesthesia
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Journal of anesthesia · Jun 2011
Randomized Controlled Trial Comparative StudyAntiemetic prophylaxis in thyroid surgery: a randomized, double-blind comparison of three 5-HT3 agents.
The aim of this double-blind randomized study was to compare the antiemetic efficacy of three 5-hydroxytryptamine type 3 antagonists in terms of the incidence and intensity of postoperative nausea and vomiting (PONV) in a homogenous group of female patients undergoing thyroidectomy. ⋯ Among the female patients of this study undergoing thyroid surgery, granisetron 3 mg provided the best prophylaxis from PONV. Ondansetron 4 mg was equally effective, but its action lasted only 6 h, whereas tropisetron 5 mg was found ineffective.
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Journal of anesthesia · Jun 2011
Randomized Controlled TrialEffects of maternal supplementary oxygen on the newborn for elective cesarean deliveries under spinal anesthesia.
The aim of this investigation was to determine whether supplementary oxygen provided by either nasal cannula or face mask versus room air might affect fetal oxygenation during elective cesarean section under spinal anesthesia by assessing maternal and neonatal regional cerebral oxygenation (rSO(2)) with a cerebral oximeter. ⋯ The effect of maternal supplementary oxygen on the newborn has been demonstrated by a cerebral oximeter monitor and supported by umbilical cord blood gas analysis and Apgar scores.
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Journal of anesthesia · Jun 2011
Randomized Controlled TrialCharacteristics of unilateral spinal anesthesia at different speeds of intrathecal injection.
Unilateral spinal anesthesia is performed to provide restriction of sympathetic and motor block. The purpose of this study is to compare the effect of different speeds of intrathecal injection on unilateral spinal anesthesia. ⋯ The result of the study show that the extra-slow injection of hyperbaric bupivacaine provided strictly unilateral sensorial and sympathetic block in 93.9 and 87.9% of the patients, respectively, and that a slow injection of low doses of hyperbaric 0.5% bupivacaine 1 ml was sufficient to provide unilateral spinal anesthesia.
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Journal of anesthesia · Jun 2011
Randomized Controlled TrialEffect of pressure-reducing devices on the quality of anterior orbit anesthesia.
Needle length is an important consideration in the safe conduct of ophthalmic blocks. A shorter needle could be used to insert the local anesthetic before the globe equator in the anterior orbit and to direct the injectable posteriorly using Honan's balloon to produce the desired effect. However, the use of pressure-reducing devices is not advisable in procedures with impaired retinal blood flow. ⋯ Ocular akinesia was assessed 10 min later; if inadequate, supplementary anesthesia was provided. No difference was detected in terms of volume injected, supplementation, and akinesia score. Under the conditions of this study, Honan's balloon did not contribute to the quality of the anterior orbit anesthesia, and the technique can be successfully used when ocular compression is contraindicated.
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Journal of anesthesia · Apr 2011
Randomized Controlled Trial Comparative StudyA randomized comparison of different doses of intrathecal levobupivacaine combined with fentanyl for elective cesarean section: prospective, double-blinded study.
Levobupivacaine may produce a sensory and motor block different from that produced by bupivacaine, which is the most popular local anesthetic in parturients undergoing cesarean section. The aim of this study was to investigate the block characteristics, the clinical efficacy, surgeon and patient satisfaction, and hemodynamic effects of using different doses of intrathecal plain levobupivacaine combined with fentanyl. ⋯ The incidence of hypotension was higher in the levobupivacaine 10 mg group, even though this group presented more effective anesthesia and greater patient and surgeon satisfaction compared with the levobupivacaine 5 and 7.5 mg groups. As a result, we believe that levobupivacaine 7.5 mg combined with fentanyl 15 μg is suitable for combined spinal-epidural anesthesia in elective cesarean section.