Annals of medicine
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Comparative Study
Right versus left thoracic approach esophagectomy for patients with neoadjuvant immunochemotherapy.
The purpose of this study was to investigate the safety and efficacy of left thoracic approach (LTA) and right thoracic approach (RTA) in patients with esophageal squamous cell carcinoma (ESCC) after neoadjuvant immunochemotherapy (NICT). ⋯ There was no difference in postoperative complications and short-term survival in patients with ESCC underwent surgery after NICT regardless of left or right thoracic approach. It is worth noting that lymphovascular invasion has an important impact on the prognosis of these patients.
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The COVID-19 pandemic, caused by SARS-CoV-2, has had profound global impacts since its emergence in late 2019. Whilst acute symptoms are well-documented, increasing evidence suggests long-term consequences extending beyond the acute phase. This study aimed to investigate the long-term cognitive and autonomic effects of COVID-19 in young adults. ⋯ Young adults who had COVID-19 infection approximately 28 months ago show minimal long-term impact on cognitive function and autonomic regulation. However, subtle cognitive inefficiencies persist, particularly in working memory and executive function tasks. These findings suggest a generally favorable long-term prognosis for young adults following mild to moderate COVID-19 but highlight the need for further investigation into persistent subtle cognitive effects and autonomic effects.
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Medical errors (MEs) significantly threaten patient safety globally. This study aimed to explore multidimensional factors associated with self-reported MEs among Chinese physicians and nurses. ⋯ Self-reported MEs are relatively common among Chinese physicians and nurses, and are associated with various factors. Poor workplace conditions and mental distress are linked to an increased risk of MEs. Implementing effective interventions to improve workplace conditions and mental health is crucial for reducing MEs.
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Maternal colonization with Group B Streptococcus (GBS) disrupts the vaginal microbiota, potentially affecting infant microbiota assembly and growth. While the gut microbiota's importance in infant growth is recognized, the specific effects of maternal GBS on growth remain unclear. This study aimed to explore the effects of maternal vaginal GBS during pregnancy on early infant growth, microbiome, and metabolomics. ⋯ GBS exposure is associated with decreased infant length growth, with altered microbiota and metabolites potentially mediating the effects of maternal GBS on offspring length growth, offering potential targets for predicting and addressing growth impairment.
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To assess the link between persistent lipoprotein(a) [Lp(a)] exposure levels and clinical outcomes in patients with acute myocardial infarction (AMI). ⋯ In AMI patients, sustained high Lp(a) levels were significantly associated with increased risk of MACCE, non-fatal stroke, unplanned revascularization, and both all-cause and cardiovascular death.