Journal of neurosurgical anesthesiology
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J Neurosurg Anesthesiol · Oct 2012
Indication for surgery and the risk of postoperative nausea and vomiting after craniotomy: a case-control study.
The primary hypothesis of the study is that acoustic neuroma (AN) surgery and microvascular decompression (MVD) of cranial nerves increase the risk of postoperative nausea and vomiting (PONV). ⋯ MVD and AN resection were associated with an increased likelihood of PONV compared with craniotomies performed for other tumor resection.
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The third PANDA symposium on Anesthesia and Neurodevelopment in Children included a session on Patient Centered Outcomes Research. Three speakers were invited to discuss SmartTots, a private-public partnership between IARS and FDA, Wake Up Safe, a patient safety organization and lastly, NICHD/NIH funding for training in research. The session provided information related to ongoing efforts to improve outcome and safety of anesthesia care in children and introduced potential sources and mechanisms of federal and non-federal funding for research related to anesthetic neurotoxicity in the developing brain.
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J Neurosurg Anesthesiol · Oct 2012
Randomized Controlled TrialPostoperative analgesic effects of wound infiltration with tramadol and levobupivacaine in lumbar disk surgeries.
Wound infiltration with local anesthetics may improve postoperative analgesia. Tramadol has been shown to have effects similar to those of local anesthetics. The purpose of this study was to investigate the effects of wound infiltration with levobupivacaine and tramadol on postoperative analgesia for lumbar discectomies. ⋯ Wound infiltration with combined levobupivacaine and tramadol resulted in elimination of postoperative analgesic demand and reduction in the incidence of side effects. We conclude that infiltration of the wound site with combined levobupivacaine and tramadol provides significantly better analgesia compared with levobupivacaine or tramadol alone.
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J Neurosurg Anesthesiol · Oct 2012
Randomized Controlled TrialFentanyl co-administration decreases the induction dose requirement of propofol in patients with supratentorial tumors and not in patients with spinal lesions.
The requirement of anesthetic drugs in a patient with an intracranial space-occupying lesion is of relevance to the neuroanesthetist. The requirement is often presumed to have reduced or at least altered. However, not much research has focused on this issue. Hence, we conducted this study to examine whether intracranial tumors reduce the induction dose of propofol in patients undergoing craniotomy based on plasma and effect site concentrations (Ce) of propofol and the effect of additional fentanyl. ⋯ Propofol dose for induction of anesthesia was significantly reduced when administered after fentanyl in patients with supratentorial tumors. Tumors per se without fentanyl coadministration do not decrease the propofol requirement for induction of anesthesia.