Journal of neurosurgical anesthesiology
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J Neurosurg Anesthesiol · Jul 2014
Randomized Controlled TrialHigher Dose Dexamethasone Increases Early Postoperative Cognitive Dysfunction.
To investigate the effects of intravenous administration of dexamethasone on early postoperative cognitive dysfunction (POCD). ⋯ Administration of higher dose of dexamethasone (0.2 mg/kg) increases the incidence of POCD in the early postoperative period after microvascular decompression under general anesthesia.
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J Neurosurg Anesthesiol · Jul 2014
Case ReportsAnesthetic Approach to High-Risk Patients and Prolonged Awake Craniotomy Using Dexmedetomidine and Scalp Block.
Awake craniotomy with intraoperative speech or motor testing is relatively contraindicated in cases requiring prolonged operative times and in patients with severe medical comorbidities including anxiety, anticipated difficult airway, obesity, large tumors, and intracranial hypertension. The anesthetic management of neurosurgical patients who possess these contraindications but would be optimally treated by an awake procedure remains unclear. ⋯ Dexmedetomidine, with concurrent scalp block, is an effective and safe anesthetic approach for awake craniotomy. Dexmedetomidine facilitates the extension procedure complexity and duration in patients who might traditionally not be considered to be candidates for this procedure.