Journal of neurosurgical anesthesiology
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J Neurosurg Anesthesiol
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J Neurosurg Anesthesiol · Jan 2018
Review Meta AnalysisSodium Bicarbonate for Control of ICP: A Systematic Review.
Our goal was to perform a systematic review of the literature on the use of intravenous sodium bicarbonate for intracranial pressure (ICP) reduction in patients with neurologic illness. ⋯ There currently exists Oxford level 4, Grading of Recommendation Assessment Development and Education D evidence to support an ICP reduction effect with intravenous sodium bicarbonate in TBI. No comments on its impact in other neuropathologic states, or on patient outcomes, can be made at this time.