Journal of neurosurgical anesthesiology
The most recent articles from:
J Neurosurg Anesthesiol
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J Neurosurg Anesthesiol · Jul 2011
Letter Case ReportsTakotsubo cardiomyopathy and the difficult airway.
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J Neurosurg Anesthesiol · Apr 2011
Neuroprotective effects and suppression of ischemia-induced glutamate elevation by β1-adrenoreceptor antagonists administered before transient focal ischemia in rats.
β-Adrenoreceptor antagonists provide neuroprotective effects after focal cerebral ischemia in experimental settings. This study was conducted to compare the neuroprotective effects of low-dose and high-dose of selective β1-adrenoreceptor antagonists in rats after focal cerebral ischemia. We also investigated whether glutamate and norepinephrine contribute to neuroprotection of the β-adrenoreceptor antagonists. ⋯ This study indicates that the improvement in neurological and histologic outcomes by selective β1-adrenoreceptor antagonists after transient focal cerebral ischemia is partly attributed to attenuation of glutamate release.