Burns : journal of the International Society for Burn Injuries
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Burn referrals make up a significant proportion of the referrals received by the on-call Plastics surgery team at University Hospital Plymouth (UHP). UHP is a burns facility that takes referrals that are< 10% total body surface area (TBSA) in adults and< 5% in children. Since switching to a telemedicine service in 2018, this has had the benefit of not needing to see the patient face-to-face. It allows for direct advice given over the phone enabling immediate treatment to be administered. In addition it prevents unnecessary referrals. The COVID-19 pandemic has meant that more people are spending time at home and this study aims to see if this has had an impact on the number of referrals received. ⋯ There was an increase in the number of referrals during COVID-19. Overall there were a very low number of inappropriate referrals. The telemedicine system has impacted positively in time efficiency especially during COVID-19. It has meant that advice can be given without seeing the patient directly leading to both benefits for the patient and the department.
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Artificial red blood cells [i.e., hemoglobin vesicles (HbVs)] can be used as photosensitizers in pulsed-dye laser (PDL) treatment for port wine stains in animal models. Small HbVs are distributed in the vicinity of the endothelial cells of the blood vessels. In our previous in vivo experiments, both HbVs and red blood cells absorbed photons of the laser and generated heat, contributing to removal of very small blood vessels and large deeper subcutaneous blood vessels with PDL irradiation. ⋯ This beneficial effect in dye laser treatment for port wine stains may be the result of the antioxidative property of CO against free radicals in the zone of stasis that may still be theoretically viable in burns. This effect of CO protecting tissues from thermal damage is consistent with previous reports of CO as a reducing agent. If the reducing agent can be delivered directly to the affected area immediately after the burn injury, even in a small amount, the complex inflammatory cascade may be reduced and unnecessary inflammation after laser treatment that lowers the patient's quality of life can be avoided.
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Burn areas are susceptible to bacterial growth and infections, particularly in cases with lengthy periods of hospital stay. Burn wound healing, which involves various molecular and cellular mechanisms, continues to be a significant problem. ⋯ In order to clarify the effects of kefir in the wound healing process, the macroscopic changes in kefir-applied scar tissue as well as wound depth and width were examined and IL-1α, IL-1β, IL-6, IL-8, IL-10 and TNF-α, VEGF, TGF-β protein levels were determined using the qRT-PCR method. The findings of the present study show that kefir has a positive impact on the factors playing a role in wound healing and accelerates the healing process.
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Multicenter Study
Establishment of the German Burn Registry - five years of prospective data collection.
From 1991-2014, all major burn centers of the German-speaking countries participated in a multicenter study in which essentially demographic data were collected. Individual patient data was located at the particular burn centers and only cumulated data were summarized annually for presentation. Retrospective statistical analysis of the entire data collection and identification of subgroups was not possible. In 2015 the German Burn Registry was established for prospective collection of individual patient data as a tool for quality management (QM) and for scientific analyses. ⋯ A registry is mandatory for quality assurance in burn medicine, since realization of randomized studies is difficult due to the heterogeneity of burn injuries. The German Burn Registry already is one of the biggest burn registries in Europe. Several scientific projects, based on the registry database, are in working process or have already been published.