Burns : journal of the International Society for Burn Injuries
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In this research, a novel semi-interpenetrating hydrogel network comprised of polyethylene glycol diacrylate (PEGDA)/polyvinyl alcohol (PVA)/tragacanth gum (TG) with adaptable mechanical, biological, and physical characteristics was fabricated for wound healing purposes. The chemical structure of the films and the surface morphology were examined by FTIR and SEM, respectively. In addition, swelling ratio, mechanical characteristics, water vapor transmission rate (WVTR), gel fraction, and degradability of the hydrogels were assessed. ⋯ The results verified the non-toxic nature of PEGDA/PVA/TG hydrogel networks. Finally, the antibacterial results demonstrated that the highest antibacterial activities against bacterial pathogens is related to the TG-containing film. Therefore, PEGDA/PVA/TG hydrogel networks can be favorable wound dressings.