Burns : journal of the International Society for Burn Injuries
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Randomized Controlled Trial
Potential therapeutic effects of topical recombinant human erythropoietin on burn wound healing: A preliminary randomized double-blind controlled clinical trial.
Burn injuries can cause significant mortality and morbidity. This study aimed to evaluate the efficiency of topical recombinant human erythropoietin (rhEPO) on enhancing burn wound healing. ⋯ At the second follow-up visit, all parameters were significantly lower in the rhEPO group compared with the control group except for itchiness. The results of the next two follow-up sessions were also the same. The total value of the modified Vancouver Scar Scale (VSS) at days 5, 7, and 14 was significantly lower in the rhEPO group compared with the routine of care group. Trial Registry Date: 2022-03-02, Trial Registry number: IRCT20190810044500N23 CONCLUSIONS: The results of the present study suggested that topical rhEPO is a potential option in burn wounds and patient satisfaction, without causing intolerable side effects.
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Severe burns are a significant cause of life-threatening conditions in both peacetime and wartime. Shock is a critical complication during the early stages of burn injury, contributing substantially to mortality and long-term disability. Effective fluid resuscitation is crucial for preventing and treating shock, with prompt administration being vital. ⋯ Based on a comprehensive review of relevant research, we present provisional guidelines for ORT in burn patients. These guidelines aim to inform clinical practice but should be applied cautiously due to limited clinical evidence. Implementation must be tailored to the patient's condition under healthcare supervision, with adjustments according to evolving circumstances: ① Initiation timing: Start as soon as possible, and the ideal start time is usually within 6 h after injury. ② Rate of application: Employing a fractional administration approach, wherein small quantities of approximately 150-250 millilitres are provided for each instance and the initial fluid rate of oral rehydration can be simplified to 100 mL/kg/24 h. ③ Composition combination: In addition to essential salts and glucose, the oral rehydration solution can incorporate various anti-inflammatory and cellular protection constituents.
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Multicenter Study
Psychological resilience and associated factors in caring for mass burn patients among rescue nurses: A cross-sectional study.
This current study explored the relationship between challenge-hindrance stressors, coping style, and psychological resilience among rescue nurses caring for mass burn patients. ⋯ In mass burns accidents, rescuer nurses have a medium level of psychological resilience, which positively and significantly correlated with challenge stressors and positive coping style. It is suggested that more attention should be devoted to the target population to formulate effective intervention plans, reduce psychological impact, and improve their capacity for coping with disasters.
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Demographic data reveal a correlative relationship between facial burns and profoundly impaired dental health, while inhalation injury correlates with a high Periodontal Screening and Recording Index, both of which significantly reduce quality of life for the burn injury patient. Despite these facts, few if any burn centers surveyed in the U. S. or Germany enlist specialized services and well-defined follow-up protocols for patients who might well be at risk. ⋯ Thermal injury patterns to perioral-related and dental structures is increasingly being recognized. This review delineates current burn-related dental health pathology and when available the underlying causation. These findings may help guide future research as well as therapeutic strategies to improve dental health and outcome for our patients.
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Multicenter Study
"To BAL or not to BAL, that is the question": Variations in smoke inhalation injury guidelines from burn units and centres in England, Scotland and Wales.
To evaluate variations in diagnostic criteria and management recommendations for smoke inhalation injury (SII) amongst the burn networks of England, Scotland, and Wales. ⋯ This study has outlined the substantial variations in guidance for the management of SII. The results underscore the need for a national guideline outlining a standardised approach to the diagnosis and management of SII, within the limitations of the current evidence.