European journal of internal medicine
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Eur. J. Intern. Med. · Feb 2020
Effects of benzodiazepines on orthostatic blood pressure in older people.
Older people taking benzodiazepines (BDZs) have higher risk of falling, which is mainly attributed to cognitive and psychomotor effects. BDZs may also have hypotensive effects. We investigated the association between BDZs and orthostatic blood pressure behaviour in older people. ⋯ Older people taking BDZs may have a higher risk of orthostatic hypotension, perhaps due to an exaggerated immediate BP drop. This adds to other BDZ-related falls risks. BDZs should be avoided in older people at risk of falling.
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Eur. J. Intern. Med. · Feb 2020
Three-month mortality in permanently bedridden medical non-oncologic patients. The BECLAP study (permanently BEdridden, creatinine CLearance, albumin, previous hospital admissions study).
To predict the 3-months mortality in permanently bedridden medical non-oncologic inpatients. ⋯ Approximately two out of three non-oncologic medical patients permanently bedridden having 2 of the abovementioned items are dead 3 months after index admission; a simple score including bedridden status, creatinine clearance, albumin, dysphagia, age and sex may help discuss management priorities.
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Eur. J. Intern. Med. · Feb 2020
Comparative influence of Acute Illness Severity and comorbidity on mortality.
The extent to which illness severity and comorbidity determine the outcome of an emergency medical admission is uncertain. We aim to quantitate the relative effect of these factors on mortality. ⋯ High AISS and Comorbidity Scores were predictive of 30-day in-hospital mortality and relatively common in emergency medical admissions. There is a strong interaction between the two scores.