European journal of internal medicine
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Eur. J. Intern. Med. · Jan 2023
Post-operative recurrence of liver cancer according to antiviral therapy for detectable hepatitis B viremia: A nationwide study.
High postoperative recurrence of hepatitis B virus (HBV)-infected hepatocellular carcinoma (HCC) remains a significant challenge. Here, we aimed to compare the postoperative HCC recurrence between patients with AVT for detectable serum HBV-DNA vs. those without. ⋯ Initiating AVT based on detectable serum HBV-DNA provided the similar risk of postoperative HCC recurrence in HBV-infected HCC patients with and without detectable serum HBV-DNA.
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Eur. J. Intern. Med. · Jan 2023
Effects and differences of sleep duration on the risk of new-onset chronic disease conditions in middle-aged and elderly populations.
Few longitude cohort studies investigated the risk of the duration of nighttime sleep and naps to the new-onset common chronic disease conditions (CDCs) in middle-aged (45-60) and the elderly (age ≥ 60) populations using an age-stratified strategy. ⋯ Nighttime sleep and daytime naps may have their own implications for the new-onset CDCs' risk in the aging process.
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Eur. J. Intern. Med. · Jan 2023
Time-trends in disease characteristics and comorbidities in patients with chronic hepatitis B in the period 1980-2020.
The incidence of chronic hepatitis B (CHB) is declining due to successful implementation of vaccination programs and widespread use of antiviral therapy. We aimed to study time-trends in disease characteristics and comorbidities in newly referred CHB patients. ⋯ Foundation for Liver and Gastrointestinal Research Rotterdam, the Netherlands and Gilead Sciences.