European journal of internal medicine
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Eur. J. Intern. Med. · Jul 2023
Sources of primary bloodstream infections in internal medicine patients - a cohort study.
To describe the sources of bloodstream infections (BSIs) in internal-medicine patients, on admission and during hospitalization, and to determine the proportion of BSIs in which no secondary cause could be defined (i.e., primary-BSI). ⋯ The proportion of primary non-CLABSI among HA-BSI events is very high (46.2%). The absence of any plausible source for these BSIs, and the fact that in our hospital more than 90% of patients in medicine wards have peripheral lines, suggests that these may be a possible source for primary non-CLABSIs. Measures to prevent peripheral-line associated BSI (PLABSI), like those implemented successfully for the prevention of CLABSI, should be considered.
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Eur. J. Intern. Med. · Jul 2023
The association between direct oral anticoagulant concentration upon acute stroke and stroke outcome.
This study aimed to investigate the association between direct oral anticoagulant (DOAC) concentration upon acute ischemic stroke (IS) or intracranial hemorrhage (ICH) and stroke outcomes. ⋯ Among DOAC users who developed IS, low drug concentrations at hospital presentation predicted poor outcomes.