European journal of internal medicine
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Coeliac disease is the most common immune-mediated enteropathy, affecting approximately 1 % of the population worldwide. Currently, the vast majority of individuals remain undiagnosed. Coeliac disease is triggered by gluten ingestion in genetically predisposed individuals carrying the human leukocyte antigen (HLA) genes; HLA-DQ2 and HLA-DQ8. ⋯ Clinicians practicing internal medicine have a unique opportunity to diagnose this multisystem autoimmune disease. By doing so, they would avoid delays in diagnosis for these patients. A low threshold for serological testing is recommended.
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Eur. J. Intern. Med. · Feb 2025
Clinical characteristics and outcomes of Takotsubo syndrome in patients with chronic obstructive pulmonary disease.
takotsubo syndrome (TTS) is an acute heart failure syndrome characterized by a relevant comorbid background, including chronic obstructive pulmonary disease (COPD). However, TTS patients with COPD are still not well characterized. ⋯ COPD marks a vulnerable TTS phenotype including higher risk of in-hospital complications, long-term recurrence and mortality.