The British journal of general practice : the journal of the Royal College of General Practitioners
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Long-term antidepressant use, much longer than recommended by guidelines, may cause harmful effects and generate unnecessary costs. ⋯ Deprescribing long-term AD is a difficult and complex process for HPs. The review found evidence that the barriers far outweigh the facilitators. More education on the lack of evidence for the long-term effect of AD and the risks of long-term use, guidance on managing long-term use, and support for HPs and patients is needed to increase long-term AD discontinuation. Further research from an HP perspective other than GPs is required and should also explore how HPs can be supported in managing discontinuation ADs.
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Prostate cancer (PCa) is the most common cancer in the UK, with 1 in 8 affected in their lifetime. However, there are significant race disparities that Black men are more negatively impacted than any other races with their increased risks and worse outcomes. However, they are under-represented in research, and often labelled as 'hard to reach' population. ⋯ Using a co-participatory approach in community research engagement was successful. We shared our knowledge, built trust, and identified research priorities.
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The evidence on the short- and long-term associations of COVID-19 with cardiovascular disease (CVD) outcomes and mortality is limited. ⋯ COVID-19 is associated with increased short- and long-term risks of CVD and mortality. Ongoing monitoring of signs and symptoms of developing cardiovascular complications post-diagnosis and up till at least a year post-recovery may benefit infected patients, especially those with severe disease.