Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Sep 2001
How do anaesthesiologists treat malignant hyperthermia in a full-scale anaesthesia simulator?
Clinical malignant hyperthermia (MH) is rare and usually occurs unexpectedly. Prompt diagnosis and correct treatment is crucial for survival of the patient developing fulminant MH. The aims of the present study were to investigate whether anaesthesiologists could make a correct diagnosis of MH and to evaluate their treatment of fulminant MH in a simulator. ⋯ All teams diagnosed MH in the simulator satisfactorily. The surprising negative finding was that more than half of the participants failed to hyperventilate the "patient" although they intended to do so. This investigation shows that the problem in these teams' treatment of MH was more a question of practical management of the resources than lack of theoretical knowledge.
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Acta Anaesthesiol Scand · Sep 2001
Intracerebral microdialysis and bedside biochemical analysis in patients with fatal traumatic brain lesions.
Microdialysis with bedside biochemical analysis was used to monitor cerebral biochemical alterations that precede and accompany increase in intracranial pressure (ICP), resulting in a complete cessation of cerebral blood flow. ⋯ Changes of cerebral energy metabolism that accompany cerebral ischaemia follow a certain pattern and may be detected at the bedside by intracerebral microdialysis before the secondary damage causes an increase in ICP.
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Acta Anaesthesiol Scand · Sep 2001
Moderate hypothermia blunts the inflammatory response and reduces organ injury after acute haemorrhage.
Reduced body temperature is a common companion to trauma/haemorrhage. Several clinical studies have identified hypothermia as an independent risk variable predisposing to increased morbidity and mortality. At the same time it is known that most enzymatic reactions are downregulated at temperatures below 37 degrees C. Theoretically this should restrain the inflammatory response and protect the host from remote organ injury. The study was performed to test this hypothesis. ⋯ Moderate hypothermia had an organ protective effect in this model of controlled haemorrhagic shock. This coincided with a significant reduction of the proximal cytokine IL-6 and reactive oxygen species, which conceivably influenced the outcome.
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Acta Anaesthesiol Scand · Sep 2001
Letter Case ReportsPost-operative pancreatitis after propofol administration.