Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Jan 2002
Randomized Controlled Trial Clinical TrialPost-operative analgesia following total knee replacement: an evaluation of the addition of an obturator nerve block to combined femoral and sciatic nerve block.
Femoral and sciatic nerve block may not provide complete post-operative analgesia following total knee replacement. This study was designed to evaluate whether the addition of an obturator nerve block to combined femoral and sciatic nerve block improves the quality of post-operative analgesia following primary total knee replacement. ⋯ The addition of an obturator nerve block to femoral and sciatic blockade improved post-operative analgesia following total knee replacement.
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Acta Anaesthesiol Scand · Jan 2002
Construction and evaluation of a manikin for perioperative heat exchange.
During surgery hypothermia can be avoided only if the heat exchange between the body surface and the environment can be controlled. To allow a systematic analysis of this heat exchange, we constructed and evaluated a copper manikin of the human body. ⋯ The excellent correlation of hRC between the volunteers and the manikin will allow the manikin to be used for standardised studies of perioperative heat exchange.
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Acta Anaesthesiol Scand · Jan 2002
The neck crease as a landmark of Chassaignac's tubercle in stellate ganglion block: anatomical and radiological evaluation.
Stellate ganglion block (SGB) is most commonly performed at the transverse process of the sixth cervical vertebra, the identification of which could be difficult in patients with short and wide necks. This study was conducted to evaluate whether the neck skin crease is a reliable indicator of the C6 level. ⋯ The studied means to identify the C6 transverse process was found to correlate well with each other (P<0.001). Since in 30% of cases the C6 process could not be identified by any of the studied means, radiological guidance is recommended in order to ensure optimal safety and efficacy of SGB in selected cases.
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Acta Anaesthesiol Scand · Jan 2002
Intrathecal administration of liposomal neostigmine prolongs analgesia in mice.
There is substantial evidence that cholinomimetic drugs increase pain threshold. However, the profound side effects of these agents have limited their clinical use either as analgesics or as analgesic adjuncts. A delivery system that would assure a slow and sustained drug release may be of value in ameliorating the problem of untoward effects. ⋯ Liposomal neostigmine provides prolonged spinal antinociception, and permits the safe administration of a relatively large dose, because drug is gradually released from the liposomal depot. This technology holds promise for the development of a clinically useful neostigmine formulation to provide spinal analgesia.