Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Jan 2006
Meta AnalysisA qualitative systematic review of peri-operative dextromethorphan in post-operative pain.
The N-methyl-D-aspartate (NMDA) receptor antagonist, dextromethorphan (DM), has received interest as an adjunctive agent in post-operative pain management. Clinical trials have been contradictory. This systematic review aims to evaluate the available literature examining the analgesic efficacy of DM in post-operative patients. ⋯ Based on the studies available, DM has the potential to be a safe adjunctive agent to opioid analgesia in post-operative pain management, but the consistency of the potential opioid-sparing and pain-reducing effect must be questioned. Consequently, it is not possible to recommend dose regimens or routine clinical use of DM in post-operative pain. The route of administration may be important for the beneficial effect.
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Acta Anaesthesiol Scand · Jan 2006
Case ReportsA case of suspected non-neurosurgical adult fatal propofol infusion syndrome.
A previously healthy woman (20 years old) was admitted to our hospital with several fractures after a car accident. She was sedated with propofol, etc. in doses ranging from 1.4 to 5.1 mg/kg/h for 88 h. She developed multiple organ failure with rhabdomyolysis and died. This case fulfils (except acidosis) the criteria of propofol-infusion syndrome (PRIS) in a young adult.
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Acta Anaesthesiol Scand · Jan 2006
Randomized Controlled Trial Comparative StudyComparison of airway management with the intubating laryngeal mask, laryngeal tube and CobraPLA by paramedical students in anaesthetized patients.
Because of the importance of airway management in emergency care, alternative methods with shorter learning curves for inexperienced personnel have been looked for as a substitute for endotracheal intubation (ETI). ⋯ Clinically inexperienced paramedical students can successfully use ILMA in anaesthetized patients. Further investigations are warranted to study whether ILMA or LT can replace ETI in emergency airway management when used by inexperienced medical or paramedical staff.
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Acta Anaesthesiol Scand · Jan 2006
Randomized Controlled TrialSupplemental 80% oxygen does not attenuate post-operative nausea and vomiting after breast surgery.
Although supplemental oxygen has been shown to be as effective as ondansetron in the prevention of post-operative nausea and vomiting (PONV) in one study in abdominal surgery patients, the antiemetic efficacy of supplemental oxygen is controversial on the basis of studies with other patients. We compared the efficacy of 80% and 30% oxygen in decreasing PONV in breast surgery. Ondansetron was used as an active control. ⋯ In this study, supplemental 80% oxygen administration failed to decrease PONV in breast surgery.
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Acta Anaesthesiol Scand · Jan 2006
Case ReportsAngioedema from angiotensin-converting enzyme (ACE) inhibitor treated with complement 1 (C1) inhibitor concentrate.
Up to seven in every 1000 patients experience angioedema from angiotensin-converting enzyme (ACE) inhibitors, even after many years of use. In 2003, every 20th Norwegian used an ACE inhibitor. ⋯ We believe that C1 inhibitor was effective in reversing the ACE inhibitor-induced angioedema in our patient.