Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Oct 2007
Randomized Controlled TrialBowel function after bowel surgery: morphine with ketamine or placebo; a randomized controlled trial pilot study.
Morphine decreases gut peristalsis, and ketamine decreases morphine use after surgery, and does not slow peristalsis. Thus, the combination should result in faster return of bowel function after surgery than morphine alone. ⋯ Low-dose ketamine was not efficacious for hastening return of bowel function, or for decreasing post-operative pain after surgery for bowel resection. It resulted in hallucinations in some patients. Those reporting hallucinations all wished to remain in the study.
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Acta Anaesthesiol Scand · Oct 2007
Randomized Controlled Trial Comparative StudyPrevention of withdrawal movement associated with injection of rocuronium in children: comparison of remifentanil, alfentanil and fentanyl.
We compared the efficacy of remifentanil, alfentanil and fentanyl in reducing withdrawal movement associated with the injection of rocuronium in children. ⋯ Remifentanil, alfentanil and fentanyl all reduced the incidence of withdrawal movement when administered 90 s before the injection of rocuronium compared with saline. Remifentanil was the most effective, followed by alfentanil. Fentanyl was less effective but significantly different from the saline in reducing withdrawal movement in children.
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Acta Anaesthesiol Scand · Oct 2007
Randomized Controlled TrialOxygenation and release of inflammatory mediators after off-pump compared with after on-pump coronary artery bypass surgery.
In a previous study, we showed that oxygenation was impaired for up to 5 day after conventional coronary artery bypass grafting (CABG). As cardiopulmonary bypass (CPB) may have a detrimental effect on pulmonary function, we hypothesized that coronary revascularization grafting without the use of CPB (OPCAB) would affect post-operative oxygenation and release of inflammatory mediators less compared with CABG. ⋯ When comparing OPCAB with CABG, oxygenation was more affected and only part of the systemic inflammatory response was attenuated.