Acta anaesthesiologica Scandinavica
-
Acta Anaesthesiol Scand · Nov 2011
Photoplethysmographic and pulse pressure variations during abdominal surgery.
Respiratory variations in pulse pressure (ΔPP) predict fluid responsiveness during mechanical ventilation. Variations in pulse oximetry plethysmography amplitude (ΔPOP) are proposed as a non-invasive alternative. Large variations in ΔPOP and poor agreement between ΔPP and ΔPOP are found in intensive care unit patients. General anaesthesia is suggested to reduce variability of ΔPOP and improve agreement between the variables. We evaluated the variability of the agreement between and the diagnostic values of ΔPP and ΔPOP during ongoing open abdominal surgery. The variability of diagnostic methods in specific clinical conditions is important, as this reflects the stability over time during which clinical decisions are made. ⋯ Analysis of raw signals during open abdominal surgery documents that the variance of ΔPOP is larger than of ΔPP, with wide limits of agreement between ΔPP and ΔPOP. The diagnostic values of ΔPP and ΔPOP are relatively poor.
-
Acta Anaesthesiol Scand · Nov 2011
Randomized Controlled TrialDose-dependent attenuation by fentanyl on cough during emergence from general anesthesia.
Although fentanyl suppresses tracheal tube-induced cough during anesthetic recovery, it has not been proven if its antitussive effect is dose dependent and complication free. The purpose of this study is to evaluate the relationship between fentanyl doses and cough suppression during emergence from sevoflurane anesthesia. ⋯ Fentanyl suppressed cough in a dose-related manner during recovery from general sevoflurane anesthesia, and 2 mcg/kg may be considered as a proper dose.
-
Acta Anaesthesiol Scand · Nov 2011
Hospital and long-term outcomes of ICU-treated severe community- and hospital-acquired, and ventilator-associated pneumonia patients.
Our purpose was to analyse the association of pneumonia types with hospital and long-term outcomes of intensive care unit (ICU)-treated pneumonia patients. ⋯ The type of pneumonia (i.e. SCAP, HAP or VAP) had no significant association with hospital mortality, whereas the SCAP patients had the lowest 1-year mortality.
-
Acta Anaesthesiol Scand · Nov 2011
Dexmedetomidine attenuates remote lung injury induced by renal ischemia-reperfusion in mice.
Renal ischemia-reperfusion (I/R) may cause acute lung injury (ALI). The mortality of combined acute kidney injury and ALI is extremely high. Dexmedetomidine, an α(2) adrenergic agonist, exerts potent anti-inflammatory and organoprotective effects in addition to its sedative and analgesic properties. We sought to elucidate whether dexmedetomidine can attenuate lung injury following renal I/R in a murine model of renal I/R. ⋯ Dexmedetomidine is capable of attenuating remote lung injury induced by renal IR via both α(2) adrenoceptors dependent and independent mechanisms.