Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Sep 2011
Randomized Controlled TrialEffect of L-carnitine on oxidative stress and platelet activation after major surgery.
The surgical/anesthesia trauma is associated with an increased production of reactive oxygen species (ROS). This enhanced oxidative stress leads to cell damage resulting in various complications such as sepsis, myocardial injury and increased mortality. The aim of this study was to investigate the role of antioxidant treatment with l-carnitine in oxidative stress and platelet activation in patients undergoing major abdominal surgery. ⋯ Our findings suggest that l-carnitine could be helpful in modulating oxidative stress and platelet activation during major abdominal surgery-dependent oxidative damage.
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Acta Anaesthesiol Scand · Sep 2011
Volume kinetics of acetated Ringer's solution during experimental spinal anaesthesia.
General anaesthesia lowers the clearance of crystalloid fluid, but the volume kinetics of such fluid throughout the duration of spinal anaesthesia has not been studied. ⋯ Acetated Ringer's solution showed the same kinetics during experimental spinal anaesthesia as when the fluid was infused alone. Hence, spinal anaesthesia is not associated with the reduced fluid clearance reported for general anaesthesia.
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Acta Anaesthesiol Scand · Sep 2011
ReviewAnaesthesia for endoscopic retrograde cholangiopancreatography.
Endoscopic Retrograde Cholangiopancreatography is used for both diagnostic and therapeutic purposes. It is relatively more complex than routine endoscopies and requires adequate patient sedation. Furthermore the patients often have co-morbidities. This article provides an overview of various anaesthetic drugs and the type of anaesthesiological support.