Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Sep 2011
Randomized Controlled TrialSevere traumatic brain injury: consequences of early adverse events.
Several factors associated with an unfavourable outcome after severe traumatic brain injury (TBI) have been described: prolonged pre-hospital time, secondary referral to a level 1 trauma centre, the occurrence of secondary insults such as hypoxia, hypotension or low end-tidal carbon dioxide (ETCO(2)). To determine whether adverse events were linked to outcome, patients with severe TBI were studied before arrival at a level 1 trauma centre. ⋯ Early adverse events before arrival at a level 1 trauma centre were without significance for outcome after severe TBI in the trauma system studied.
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Acta Anaesthesiol Scand · Sep 2011
Randomized Controlled TrialEffect of N-acetylcysteine on cardiac injury and oxidative stress after abdominal aortic aneurysm repair: a randomized controlled trial.
Several studies have reported that the antioxidant properties of N-acetylcysteine (NAC) can provide cardiac protection through scavenging of free radicals. The present study was aimed to assess the efficacy of NAC for cardiac protection in patients undergoing elective abdominal aortic aneurysm (AAA) repair. ⋯ NAC infusion provided cardiac protection through scavenging of oxygen free radicals.
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Acta Anaesthesiol Scand · Sep 2011
Corticosteroid therapy in intensive care unit patients with PCR-confirmed influenza A(H1N1) infection in Finland.
To evaluate the incidence, treatment, and outcome of influenza A(H1N1) in Finnish intensive care units (ICUs) with special reference to corticosteroid treatment. ⋯ The majority of H1N1 patients in ICUs received ventilatory support. Corticosteroids were administered to more than half of the patients. Despite being more severely ill, patients given corticosteroids had comparable hospital outcome with patients not given corticosteroids.
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Acta Anaesthesiol Scand · Sep 2011
Randomized Controlled TrialIncreased lung clearance of isoflurane shortens emergence in obesity: a prospective randomized-controlled trial.
There is a concern that obesity may play a role in prolonging emergence from fat-soluble inhalational anaesthetics. We hypothesized that increased pulmonary clearance of isoflurane will shorten immediate recovery from anaesthesia and post-anaesthesia care unit (PACU) stay in obese patients. ⋯ Increasing alveolar ventilation enhances anaesthetic elimination and accelerates short-term recovery in obese patients.