Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Jan 2012
Randomized Controlled TrialA randomized trial on elderly laypersons' CPR performance in a realistic cardiac arrest simulation.
Bystander cardiopulmonary resuscitation (CPR) is important for survival after cardiac arrest. We hypothesized that elderly laypersons would perform CPR poorer in a realistic cardiac arrest simulation, compared to a traditional test. ⋯ Elderly lay people are capable of performing chest compressions with acceptable quality for ten minutes in a realistic cardiac arrest simulation. Ventilation quality and hands-off time were not adequate in either group.
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Acta Anaesthesiol Scand · Jan 2012
Correlation between cardiac output and reversibility of rocuronium-induced moderate neuromuscular block with sugammadex.
The aim of this study was to evaluate the correlation between cardiac output (CO) and reversibility of rocuronium-induced moderate neuromuscular block with sugammadex in elderly patients. ⋯ The time to reach a TOF ratio of 0.9 following sugammadex is dependent on CO in elderly patients.
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Acta Anaesthesiol Scand · Jan 2012
Low-dose transdermal buprenorphine - long-term use and co-medication with other potentially addictive drugs.
Recently, low-dose transdermal buprenorphine (LD-TD-BUP) was introduced for treatment of patients with chronic non-malignant pain. The primary aim of this study was to determine the proportion of patients who were prescribed LD-TD-BUP for non-malignant pain who became long-term users. The secondary aim was to determine the proportion of patients who co-medicated with other opioids or benzodiazepines during treatment with LD-TD-BUP. ⋯ Three years after introduction, 0.4% of the Norwegian population had been dispensed LD-TD-BUP. Only one-fifth had become long-term users. Those who used opioids before the first dispension of LD-TD-BUP co-medicated with other potentially addictive drugs to a much higher degree compared with those who were opioid naive.
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Acta Anaesthesiol Scand · Jan 2012
Neutrophil inhibition contributes to cardioprotection by postconditioning.
Postconditioning (postcon) reduces infarct size, myocardial superoxide ((•)O(2)) generation, and neutrophil (PMN) accumulation. It is unknown whether inhibition of PMNs influence cardioprotection by postcon. The present study tested the following hypotheses: (1) myocardial salvage by postcon is modified by inhibition of PMNs and (2) postcon directly inhibits PMN (•)O(2) generation. ⋯ These data imply PMN involvement in cardioprotection by postconditioning.
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Acta Anaesthesiol Scand · Jan 2012
A standardized protocol for the perioperative management of myasthenia gravis patients. Experience with 110 patients.
Video-assisted thoracoscopic extended thymectomy (VATET) is well established in the treatment of myasthenia gravis; however, patient selection remains controversial. Perioperative management protocol is lacking, and concerns regarding post-operative myasthenic crisis still remain. We performed a retrospective observational study evaluating the impact of the introduction of a protocol in the perioperative management of patients with myasthenia gravis who underwent VATET. ⋯ Although the application of our protocol results in a substantial reduction in the recovery of patients in the ICU and in hospital costs, there was no substantial difference in mortality and morbidity between patients admitted to the surgical ward or to ICU.