Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Jan 2013
Randomized Controlled Trial Comparative StudyEmergence agitation in children undergoing adenotonsillectomy: a comparison of sevoflurane vs. sevoflurane-remifentanil administration.
Sevoflurane is widely used in paediatric anaesthesia but frequently causes emergence agitation (EA). This study evaluated whether limiting the sevoflurane concentration by combining remifentanil with sevoflurane reduced the incidence of EA. ⋯ The incidence of EA was lower in children undergoing adenotonsillectomy who received a lower concentration of sevoflurane combined with remifentanil than in those given a higher concentration of sevoflurane without remifentanil.
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Acta Anaesthesiol Scand · Jan 2013
Multicenter StudyHypersensitivity reactions to Patent Blue V in breast cancer surgery: a prospective multicentre study.
An increasing number of immediate hypersensitivity reactions (HSR) have been reported after the use of Patent Blue V (PBV) for breast cancer surgery. This is the first study to publish prospective data with systematic allergological assessment. ⋯ An incidence rate of one in 300 HSR to PBV was observed for patients exposed to PBV during sentinel lymph node detection. This rate is higher than rates reported after the use of neuromuscular blocking agents, latex or antibiotics.
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Acta Anaesthesiol Scand · Jan 2013
Vital dysfunctions after intensive care discharge: prevalence and impact on patient outcome.
Patients discharged from the intensive care unit (ICU) are at increased risk for serious adverse events (SAEs). Recording vital functions and comprehending the consequences of altered vitals on general wards may be suboptimal. This potentially endangers recovery after successful intensive care. We aimed to determine the prevalence of vital dysfunctions after ICU discharge and their effect on patient outcome. ⋯ Simple vital function measurement and attending ward nurse's subjective assessment facilitate early detection of post-ICU patients at risk. The threshold in seeking assistance through MET remains high.
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Acta Anaesthesiol Scand · Jan 2013
Open-heart surgery increases cerebrospinal fluid levels of Alzheimer-associated amyloid β.
Neurocognitive dysfunction occurs frequently after open-heart surgery. It has been suggested that cognitive decline after cardiac surgery with cardiopulmonary bypass (CPB) could be a functional consequence of Alzheimer's disease (AD)-like neuropathological changes. The aim of the present study was to evaluate the cerebrospinal fluid (CSF) levels of amyloid β peptide (Aβ(1-42) ) and soluble fragments of amyloid precursor protein (sAPP) as well as the cerebral inflammatory response to open-heart surgery. ⋯ Cardiac surgery with CPB causes a profound cerebral inflammatory response, which was accompanied by increased post-operative CSF levels of the AD biomarker Aβ(1-42) . We hypothesize that these changes may be relevant to Alzheimer-associated amyloid build-up in the brain and cognitive dysfunction after cardiac surgery with CPB.
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The following article from Acta Anaesthesiologica Scandinavica "Haemodynamics and cerebral oxygenation during arthroscopic shoulder surgery in beach chair position under general anaesthesia" by Jeong H, Lee SH, Jang EA, Chung SS, Lee J, Yoo KY. Acta Anaesthesiol Scand. 56 (7): 872–9(August 2012). DOI: 10.1111/j.1399-6576.2012.02716.x. and published online on 10 May 2012 in Wiley Online Library (wileyonlinelibrary.com) has been retracted at the request of the Editor-in-Chief Lars S. ⋯ Anesthesiology; 116 (5): 1047–56 (May 2012) from the same institution. The two articles do not cite each other. The corresponding author has acknowledged that data from some patients appear in both articles and the study design was misrepresented.