Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Nov 2015
Crew Resource Management in the Intensive Care Unit: a prospective 3-year cohort study.
Human factors account for the majority of adverse events in both aviation and medicine. Human factors awareness training entitled "Crew Resource Management (CRM)" is associated with improved aviation safety. We determined whether implementation of CRM impacts outcome in critically ill patients. ⋯ Our data indicate an association between CRM implementation and reduction in serious complications and lower mortality in critically ill patients.
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Acta Anaesthesiol Scand · Nov 2015
Whole blood glutathione status and ICU morbidity in critically ill children.
A high reduced glutathione ratio is associated with high mortality in adult ICU patients. Whole blood glutathione status in critically ill children is less well characterized. In this study, whole blood glutathione status in pediatric intensive care (PICU) patients was determined and the relation between the redox status of whole blood glutathione and morbidity was investigated. ⋯ A high reduced glutathione ratio was associated with longer PICU stay, duration of mechanical ventilation, and multiple organ failure.
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Acta Anaesthesiol Scand · Nov 2015
Effect-site concentration of remifentanil for attenuating QTc interval prolongation following intubation in hypertensive female patients.
Haemodynamic changes after sympathetic stimuli like tracheal intubation are more pronounced in hypertensive patients than in normotensive patients. Heart rate (HR)-corrected QT (QTc) interval changes related to intubation may also be more prominent in hypertensive patients. We hypothesised that there would be a difference in the effect-site concentration (Ce) of remifentanil to attenuate QTc interval prolongation in normotensive and hypertensive patients following intubation. ⋯ The Ce of remifentanil required to attenuate QTc interval prolongation following intubation was significantly higher in hypertensive patients than it was in normotensive patients. Thus, more caution should be taken related to QTc interval prolongation when intubating hypertensive patients.
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Acta Anaesthesiol Scand · Nov 2015
Validation of the Danish-language chronic pain acceptance questionnaire.
The Chronic Pain Acceptance Questionnaire (CPAQ, 20 items) measures patients' acceptance of chronic pain. This questionnaire has demonstrated good psychometric qualities and versions have been validated in several different languages. This study describes the validation of the Danish version of the CPAQ. ⋯ The psychometric properties of the Danish version of the 20-item CPAQ were satisfactory, showing that the Danish version of CPAQ is valid and reliable.
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Acta Anaesthesiol Scand · Nov 2015
Colloid osmotic pressure and extravasation of plasma proteins following infusion of Ringer's acetate and hydroxyethyl starch 130/0.4.
During fluid infusion therapy, plasma proteins are diluted and leak from the intravascular space, which alters the colloid osmotic pressure (COP) and potentially affects coagulation. We hypothesised that acetated Ringer's and starch solution, alone or in combination, influence these mechanisms differently. ⋯ The starch increased COP and only minor capillary leak occurred in healthy volunteers. The fluid-induced plasma dilution correlated with mild impairment of the extrinsic coagulation pathway but not of the intrinsic pathway.