Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Jan 2015
Multicenter StudyPredictive value of NGAL for use of renal replacement therapy in patients with severe sepsis.
The predictive value of plasma and urine neutrophil gelatinase-associated lipocalin (NGAL) for use of renal replacement therapy (RRT) and acute kidney injury (AKI) is not established in patients with severe sepsis. ⋯ In ICU patients with severe sepsis, plasma and urine NGAL had low predictive power for use of RRT, AKI and 90-day mortality. These results were supported by sensitivity and exploratory analyses.