Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Nov 2016
Randomized Controlled TrialTransversus abdominis plane block or intravenous lignocaine in open prostate surgery: a randomized controlled trial.
Transversus abdominis plane block (TAP) and intravenous lignocaine are two analgesic techniques frequently used after abdominal surgery. We hypothesized that these two techniques improve post-operative analgesia after open prostate surgery and sought to compare their efficacy on immediate post-operative outcome after open prostate surgery. ⋯ Our study suggests that TAP block and intravenous lignocaine do not improve the post-operative analgesia provided by systematic administration of paracetamol after open prostatectomy.
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Acta Anaesthesiol Scand · Nov 2016
Capnocytophaga canimorsus bacteremia: clinical features and outcomes from a Helsinki ICU cohort.
Capnocytophaga canimorsus is a gram-negative rod capable of causing severe sepsis or septic shock. We studied the characteristics of patients with C. canimorsus bacteremia treated in intensive care unit (ICU). ⋯ Capnocytophaga canimorsus infection may present with severe sepsis or septic shock with organ dysfunction, most frequently coagulopathy and acute kidney injury. Previously recognized risk factors are not always present. A dog in a household may be a sufficient exposure for developing a severe form of the disease. The possibility of C. canimorsus infection should be considered in patients with any contact with dogs, even in immunocompetent patients.
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Acta Anaesthesiol Scand · Nov 2016
Standard dosing of piperacillin and meropenem fail to achieve adequate plasma concentrations in ICU patients.
Controversies remain regarding optimal dosing and the need for plasma concentration measurements when treating intensive care patients with beta-lactam antibiotics. ⋯ With standard doses of meropenem and piperacillin-tazobactam, plasma concentrations in ICU patients vary > 10-fold and are suboptimal in a significant percentage of patients. The variation is large also between patients with similar renal function.