Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Nov 2017
Review Meta Analysis Comparative StudyTherapeutic bronchoscopy vs. standard of care in acute respiratory failure: a systematic review.
We aimed to assess patient-important benefits and harms of therapeutic bronchoscopy vs. standard of care (no bronchoscopy) in critically ill patients with acute respiratory failure (ARF). ⋯ The quantity and quality of evidence supporting therapeutic bronchoscopy in critically ill patients with ARF is very low with no firm evidence for benefit or harm.
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Acta Anaesthesiol Scand · Nov 2017
Randomized Controlled TrialPregabalin reduces opioid consumption and hyperalgesia but not pain intensity after laparoscopic donor nephrectomy.
Gabapentinoids are increasingly used to reduce acute postoperative pain, opioid consumption and opioid-related adverse effects. We explored the opioid-sparing, analgesic and anti-hyperalgesic effect of perioperative administered pregabalin in laparoscopic living donor nephrectomy. ⋯ Perioperative pregabalin added to a multimodal analgesic regimen was opioid-sparing, but made no difference to pain intensity score 0-48 h after surgery. Pregabalin may reduce incisional hyperalgesia on the first day after surgery.
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Acta Anaesthesiol Scand · Nov 2017
Assessment of plasma endostatin to predict acute kidney injury in critically ill patients.
We evaluated whether plasma endostatin predicts acute kidney injury (AKI), need for renal replacement therapy (RRT), or death. ⋯ Endostatin increases with AKI severity but has limited value as a predictor of AKI, RRT and 90-day mortality in patients admitted to ICU. Moreover, endostatin does not improve AKI risk prediction when added to a clinical risk model.