Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · May 2019
Intrathecal betamethasone for cancer pain: A study of its analgesic efficacy and safety.
A preliminary study has shown effective cancer pain relief by intrathecal betamethasone (ITB). However, further evidence is needed to support this new approach. ⋯ Intrathecal injection of betamethasone produced analgesia for opioid-resistant cancer pain, and may be a potent therapeutic option for intolerable pain from vertebral column and/or surrounding nerve plexus metastases.
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Acta Anaesthesiol Scand · May 2019
Measuring pain-Physiological and self-rated measurements in relation to pain stimulation and anxiety.
The aim of the present study was to investigate how emotions influence pain, measured by one subjective self-rated measure, the numeric rating scale (NRS), and one objective physiological measure, the number of skin conductance responses (NSCR). ⋯ The NRS was strongly influenced by affective state, with higher pain ratings during more anxiety-like states, whereas NSCR correlated to the strength of electrical pain stimulation. That reported pain is moderated by anxiety, puts forward a discussion whether reduction of the anxiety level should be considered during analgesia treatment.