Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Apr 2021
Retraction Of PublicationRetraction: Röhm KD, Riechmann J, Boldt J, Schöllhorn T, Piper SN. Do patients profit from physostigmine in recovery from desflurane anaesthesia? Acta Anaesthesiol Scand. 2007;51(3):278-83. https://doi.org/10.1111/j.1399-6576.2006.01238.x.
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Acta Anaesthesiol Scand · Apr 2021
ReviewAntioxidant treatment to reduce mortality and serious adverse events in adult surgical patients: A systematic review with meta-analysis and trial sequential analysis.
Hyperoxia during anesthesia can increase cellular oxidative stress, and perioperative antioxidant treatment may reduce the resulting damage. The aim of this review was to evaluate risks and benefits of antioxidant treatment in surgical patients. We hypothesized that antioxidant treatment reduced mortality compared to placebo/no intervention. ⋯ We found a 26% relative risk reduction of mortality in surgical patients treated with antioxidants but the quality of evidence supporting our findings is low and influenced by clinical heterogeneity and high risk of systematic- and random errors.
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Acta Anaesthesiol Scand · Apr 2021
ReviewFluid escapes to the "third space" during anesthesia, a commentary.
The "third fluid space" is a concept that has caused much confusion for more than half a century, dividing anesthesiologists into believers and non-believers. ⋯ During anesthesia and surgery one third of the infused crystalloid fluid is at least temporarily unavailable for excretion, which probably contributes to postoperative weight increase and edema.
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Acta Anaesthesiol Scand · Apr 2021
ReviewPre-procedural platelet transfusion thresholds in hospitalised children - protocol for a scoping review.
Thrombocytopenia is a common condition in hospitalised critically ill children and most platelet transfusions are given as prophylaxis to non-bleeding children prior to invasive procedures such as central venous catheterisation and lumbar puncture. Platelet transfusion may reduce bleeding complications but have also been associated with potential adverse effects and variation in clinical practice exist. To direct future research, we aim to assess the current evidence regarding prophylactic platelet transfusion prior to procedures in hospitalised thrombocytopenic children. ⋯ The outlined scoping review will provide an overview on the benefits and harms of prophylactic platelet transfusion prior to invasive procedures in thrombocytopenic hospitalised children.