Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Feb 2000
Influence of acute normovolaemic haemodilution on the dose-response and time-course of action of atracurium.
Acute normovolaemic haemodilution is a common method to save and avoid homologous blood transfusion during surgery. The aim of this study was to evaluate the influence of acute isovolaemic haemodilution on the dose-response and time-course of action of atracurium. ⋯ We concluded that the patients undergoing acute isovolaemic haemodilution were about 30% more sensitive to neuromuscular blockade of atracurium and had a longer duration after administration of the same dose (microg/kg) than the control patients. Care must be taken with this problem when atracurium is used as a muscle relaxant during acute haemodilution.
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Acta Anaesthesiol Scand · Feb 2000
Coronary and systemic hemodynamic effects of clevidipine, an ultra-short-acting calcium antagonist, for treatment of hypertension after coronary artery surgery.
The aim was to evaluate the use of clevidipine, a new vascular selective, ultra-short-acting calcium antagonist for blood pressure control after coronary artery bypass grafting (CABG). ⋯ Clevidipine rapidly reduced MAP and induced a systemic, pulmonary and coronary vasodilation with no effect on venous capacitance vessels or HR. Clevidipine caused no adverse effects on myocardial lactate metabolism. Clevidipine thus appears suitable to control blood pressure after CABG.
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Acta Anaesthesiol Scand · Feb 2000
Retracted PublicationComposition of the editorial/advisory boards of major English-language anesthesia/critical care journals.
Publications represent a central part of the research process. An analysis of who is responsible for acceptance of publications in major English-language anesthesia/critical care medicine journals was carried out. ⋯ Most editors/editorial board members of important Anesthesiology, Emergency and Critical Care journals came from the USA. Other countries play a significantly less influential role even in journals which are characterised as 'International Journals'.
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Acta Anaesthesiol Scand · Feb 2000
Randomized Controlled Trial Clinical TrialNeedle design does not affect the success rate of spinal anaesthesia or the incidence of postpuncture complications in children.
In adults, pencil-point spinal needles are believed to be less traumatic and therefore to be superior compared to cutting-point needles with respect to success rate and postpuncture complications. The aim of this randomised, parallel groups and prospective study was to record the success rate and to evaluate the incidence of complications following spinal anaesthesia with the two types of needles in children. ⋯ Both types of spinal needles can be used in children, and a free aspiration of CSF results in a high success rate of the spinal block. Postpuncture complications are as common in children as in adults.
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Acta Anaesthesiol Scand · Jan 2000
Randomized Controlled Trial Clinical TrialThe effects of clonidine on ropivacaine 0.75% in axillary perivascular brachial plexus block.
The new long-acting local anesthetic ropivacaine is a chemical congener of bupivacaine and mepivacaine. The admixture of clonidine to local anesthetics in peripheral nerve block has been reported to result in a prolonged block. The aim of the present study was to evaluate the effects of clonidine added to ropivacaine on onset, duration and quality of brachial plexus block. ⋯ The addition of clonidine to ropivacaine 0.75% does not lead to any advantage of block of the brachial plexus when compared with pure ropivacaine 0.75%.