Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Jan 1998
Randomized Controlled Trial Comparative Study Clinical TrialDesflurane versus propofol maintenance for outpatient laparoscopic cholecystectomy.
The aims of the study were to evaluate costs and clinical characteristics of desflurane-based anaesthetic maintenance versus propofol for outpatient cholecystectomy. ⋯ We conclude that desflurane is cheaper and has a more rapid emergence than propofol for outpatient cholecystectomy. However, propofol results in less pain and nausea in the recovery unit. Despite ondansetron and droperidol prophylaxis, there was still a substantial amount of nausea and vomiting after desflurane.
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Acta Anaesthesiol Scand · Jan 1998
Randomized Controlled Trial Comparative Study Clinical TrialPreoperative anxiolysis with minimal sedation in elderly patients: bromazepam or clorazepate-dipotassium?
In elderly patients undergoing ophthalmic surgery the loss of co-operation due to over-sedation, induced by drugs given preoperatively, may jeopardise the success of microsurgery performed under regional anaesthesia. The aim of this study was to compare the psychotropic effects of bromazepam and clorazepate-dipotassium, two benzodiazepines with predominantly anxiolytic and only weak sedative action. ⋯ Bromazepam is superior to clorazepate in its anxiolytic action and suitable as preoperative medication in the elderly patient because of lack of overt sedative effects.
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Acta Anaesthesiol Scand · Jan 1998
Randomized Controlled Trial Comparative Study Clinical TrialOculocardiac reflex and postoperative vomiting in paediatric strabismus surgery. A randomised controlled trial comparing four anaesthetic techniques.
Oculocardiac reflex (OCR) and postoperative vomiting are major complications of paediatric strabismus surgery. ⋯ Thiopental-isoflurane-air/O2-alfentanil resulted in a moderate risk of vomiting. Adding ondansetron significantly decreased this risk, but 6 children have to be treated for one to benefit in the early postoperative period. Propofol and propofol-lignocaine showed no benefit on vomiting but significantly increased the risk of an OCR despite high-dose prophylactic atropine.
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Acta Anaesthesiol Scand · Jan 1998
Randomized Controlled Trial Clinical TrialNausea and vomiting after major arthroplasty with spinal anaesthesia including morphine: a randomised trial of subhypnotic propofol infusion as prophylaxis.
Postoperative nausea and vomiting (PONV) following major arthroplasty with spinal anaesthesia and intrathecal morphine is reported in 45-74% of patients. This randomised, double-blind, placebo-controlled trial was undertaken to determine whether a subhypnotic infusion of propofol has a prophylactic antiemetic effect in this patient population. ⋯ These results suggest that routine use of postoperative, subhypnotic propofol infusion as PONV prophylaxis is not justified in this patient population.
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Acta Anaesthesiol Scand · Jan 1998
Randomized Controlled Trial Clinical TrialPropofol sedation and gastric emptying in volunteers.
The purpose of this study was to evaluate the effects of light propofol sedation on gastric emptying and orocecal transit time (OCT). ⋯ This study in volunteers has shown that gastric emptying of liquids seems uninfluenced by light propofol sedation. OCT was slightly prolonged during light propofol sedation.