Journal of cardiovascular electrophysiology
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J. Cardiovasc. Electrophysiol. · Oct 2013
Comparative StudyCardiovascular implantable electronic device implantation with uninterrupted dabigatran: comparison to uninterrupted warfarin.
While continuation of oral anticoagulation (OAC) with warfarin may be preferable to interruption and bridging with heparin for patients undergoing cardiovascular implantable electronic device (CIED) implantation, it is uncertain whether the same strategy can be safely used with dabigatran. ⋯ The incidence of bleeding complications is similar during CIED implantation with uninterrupted D or W. The risks are higher when OAC is combined with antiplatelet drugs.
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J. Cardiovasc. Electrophysiol. · Oct 2013
Increased preoperative serum apoptosis marker fas ligand correlates with histopathology and new-onset of atrial fibrillation in patients after cardiac surgery.
We evaluated if preoperative serum apoptosis markers correlate with atrial histological remodeling and postoperative atrial fibrillation (POAF) after cardiac surgery. ⋯ Preoperative evaluation of serum apoptosis marker Fas is useful to identify patients at risk for POAF undergoing cardiac surgery. Fas but not TRAIL correlates with the documented degree of atrial apoptosis and atrial fibrosis in RAA tissue. Further studies need to identify the prospective role of Fas in predicting POAF events.
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J. Cardiovasc. Electrophysiol. · Sep 2013
Combined dominant frequency and complex fractionated atrial electrogram ablation after circumferential pulmonary vein isolation of atrial fibrillation.
Atrial substrates with high-dominant frequency (DF) and complex fractionated atrial electrogram (CFAE) sites have sources maintaining atrial fibrillation (AF) and are potential AF ablation targets. This study aimed to evaluate an approach of circumferential pulmonary vein isolation (PVI) followed by a DF and CFAE site ablation. ⋯ A combined high-DF and continuous CFAE site ablation in all chambers after circumferential PVI may be effective in the paroxysmal and persistent AF patients.
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J. Cardiovasc. Electrophysiol. · Sep 2013
The spatial distribution of atrial fibrillation termination sites in the right atrium during complex fractionated atrial electrograms-guided ablation in patients with persistent atrial fibrillation.
The role of right atrial (RA) ablation guided by complex fractionated atrial electrograms (CFAE) in atrial fibrillation (AF) has been debated. This study evaluated the spatial distribution of RA CFAE, the critical sites, and the predictors of successful termination of longstanding persistent AF during RA ablation. ⋯ A half of patients with persistent AF refractory to LA ablation successfully converted to AT or SR during automated CFAE-guided ablation at the RA. The most common critical sites for AF termination were the CT and RA appendage and septum. Patients with AF termination during procedure whether LA CFAE only or after RA CFAE ablation had better outcome with less late recurrence of atrial tachyarrhythmia compared to those without AF termination.