Journal of cardiovascular electrophysiology
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J. Cardiovasc. Electrophysiol. · Jan 2009
Long- and short-term temporal stability of complex fractionated atrial electrograms in human left atrium during atrial fibrillation.
Complex fractionated atrial electrograms (CFAEs) have been reported as targets for catheter ablation of atrial fibrillation (AF). However, the temporal stability of CFAE sites remains poorly defined. ⋯ CFAEs recorded in the LA during AF display high temporal stability in patients with persistent AF. The clinical significance of our findings warrants further investigation.
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J. Cardiovasc. Electrophysiol. · Jan 2009
Clinical TrialA prospective pediatric clinical trial of digital music players: do they interfere with pacemakers?
There has been recent concern in the media about iPod interference with pacemakers. We systematically tested two types of digital music players (DMP) on pacemaker or ICD function in children. ⋯ Interference with pacemaker function could not be shown with iPod or MP3 players. No additional precaution beyond standard is necessary for patients with pacemakers when they are using these players.
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J. Cardiovasc. Electrophysiol. · Dec 2008
Cell membrane stretch and chest blow-induced ventricular fibrillation: commotio cordis.
Commotio cordis, sudden cardiac death secondary to blunt nonpenetrating chest blows in sports, is reported with increasing frequency. In a swine model, ventricular fibrillation (VF) is induced by a baseball blow to the chest, and the initiation of VF is related to the peak left ventricular (LV) pressure produced by the blow. LV pressure changes likely result in cell membrane stretch and mechanical activation of ion channels. Disruption of cell cytoskeleton that anchors the cell membrane prior to precordial blows offers the opportunity to explore whether cell membrane deformation is critical to commotio cordis. ⋯ The initiation of VF by chest blows is significantly increased by selective disruption of the cytoskeleton, suggesting that mechanical deformation of the cell membrane is fundamental to the activation of ion channels and underlies the mechanism of VF in commotio cordis.
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J. Cardiovasc. Electrophysiol. · Dec 2008
Full-color direct visualization of the atrial septum to guide transseptal puncture.
Transseptal puncture is required for many interventional procedures but has a serious complication rate of approximately 1%-primarily related to misidentification of the fossa ovalis resulting in inadvertent puncture of other cardiac structures. We investigated the utility of a full color visualization catheter to correctly position and guide transseptal puncture of the fossa ovalis. ⋯ The IRIS catheter allows direct in vivo visualization of the interatrial septum to guide transseptal puncture of previous punctures.
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J. Cardiovasc. Electrophysiol. · Nov 2008
Controlled Clinical TrialIntracardiac echo-guided radiofrequency catheter ablation of atrial fibrillation in patients with atrial septal defect or patent foramen ovale repair: a feasibility, safety, and efficacy study.
Intracardiac Echo-Guided Radiofrequency Catheter. ⋯ Percutaneous AF ablation using double transseptal access is feasible, safe, and efficacious in patients with ASD and PFO repairs.