Archives of orthopaedic and trauma surgery
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Arch Orthop Trauma Surg · Jul 2009
A novel model to study metaphyseal bone healing under defined biomechanical conditions.
Experimental studies on metaphyseal fractures are rare and do not control the biomechanical conditions in the healing zone. This study aimed to develop an improved experimental model, which characterizes and controls the biomechanical condition in the fracture gap of a metaphyseal fracture. ⋯ This metaphyseal bone-healing model provides defined and adjustable biomechanical conditions. The histological images demonstrated intramembranous and endochondral bone healing in the osteotomy gap without callus formation. The model therefore seems appropriate to study metaphyseal bone healing under differing mechanical conditions.
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Arch Orthop Trauma Surg · Jul 2009
Surgical treatment for local control of extremity and trunk desmoid tumors.
Surgical treatment has been the mainstay for extremity and trunk desmoid tumors with a negative surgical margin. However, even when resection with a wide surgical margin is achieved, the local recurrence rate remains high. The purpose of this study was to analyze the clinical outcome of patients with extremity and trunk desmoid tumors after surgical treatment and to determine the factors influencing local recurrence. ⋯ These results suggest that radical surgical treatment causing severe functional impairment should be avoided in selected cases on the basis of patient characteristics, and that other novel therapeutic tools may be necessary for patients in whom a higher risk of local recurrence is assumed or severe complications after surgical treatment are predicted.