Archives of orthopaedic and trauma surgery
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Arch Orthop Trauma Surg · Mar 2014
Comparative StudyPlatelet-rich plasma for enhancing surgical rotator cuff repair: evaluation and comparison of two application methods in a rat model.
Platelet-rich plasma (PRP) is a natural concentrate of autologous growth factors now being widely tested in different fields of medicine for its potential in enhancing the regeneration of tissue with low healing potential. However, studies of PRP in enhancing rotator cuff repair have been contradictory, perhaps because of how PRP is administered. The purpose of this study is to evaluate the effect of PRP and compare two different application methods of PRP on rotator cuff healing. ⋯ The application of PRP, independent of the application method, significantly improved biomechanical properties at the rotator cuff tendon-bone interface. The type of application, injection or absorption from a sponge did not influence the effect of PRP on rotator cuff healing.