Archives of orthopaedic and trauma surgery
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Arch Orthop Trauma Surg · Aug 2023
The effect of ITLN1, XCL2 and DOT1L variants on knee osteoarthritis risk in the Han population.
Knee osteoarthritis (KOA) is a complex multifactorial disease, in which genetic factors account for 50% of the risk of osteoarthritis. This study investigated the association between ITLN1, XCL2 and DOT1L variants and KOA risk in the Han population. ⋯ In short, ITLN1 rs2274908, XCL2 rs4301615 and DOT1L rs3815308 were related to KOA risk in the Han population, which was helpful to clarify the pathogenesis of these sites in KOA.
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Arch Orthop Trauma Surg · Aug 2023
Review Meta AnalysisLimb salvage versus primary amputation in Gustilo-Anderson IIIB and IIIC tibial fractures: a systematic review and meta-analysis.
The last systematic review on this topic was published in 2008. With advances in surgical techniques, patients with mangled extremities may now be potentially salvageable with comparable outcomes. This review aims to evaluate the outcomes of limb salvage compared to primary amputation in patients with severe open tibial fractures. ⋯ III.
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Arch Orthop Trauma Surg · Aug 2023
Review Meta AnalysisThe course of knee extensor strength after total knee arthroplasty: a systematic review with meta-analysis and -regression.
Muscular strength loss and atrophy are postoperative complications. This systematic review with meta-analysis investigated the course of on knee extensor mass and strength from pre-surgery over total knee arthroplasty to rehabilitation and recovery. ⋯ We found moderate certainty evidence that deficits in muscle strength of the knee extensors persist and progress until 3 months post-total knee arthroplasty in patients with end-stage knee osteoarthritis. Very low certainty evidence exists that preoperatively existing imbalance of muscle strength and mass in favor of the leg not undergoing surgery is not recovered within 1 year after surgery.
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Arch Orthop Trauma Surg · Aug 2023
Review Meta AnalysisSurgical treatment options for plantar fasciitis and their effectiveness: a systematic review and network meta-analysis.
To date, there are no systematic reviews on the utility of surgical management for plantar fasciitis to guide best practice. This review aimed to evaluate the operative options for plantar fasciitis and their effectiveness. ⋯ Level III.