Archives of orthopaedic and trauma surgery
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Humic substances are polyphenolic compounds. They have antiviral as well as desmutagenic effects and react with biopolymers such as collagen; thereby they have no toxic side effects by oral administration. ⋯ As humic substances increase the mechanical and chemical resistance of collagen fibres and promote their "maturity", it seems likely that this effect of humic substances depends upon their interaction with the hydrogen bonding and covalent bonding of the collagen fibres. Such a conclusion is confirmed by the results of X-ray diffraction analysis.
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Arch Orthop Trauma Surg · Jan 1992
Autogenously vascularised bone allografts. Experimental model of a new bone-muscle composite graft.
Conventional bone allografts carry a high incidence of complications such as infections and pseudarthroses due to immunological rejection and avascularity of grafts. In vascularised grafts healing and remodelling of bone is quicker and more complete. However, vascularised allografts need immunosuppression for prevention of rejection with vascular occlusion. ⋯ A higher number of osteocytes were found in the autogenously vascularised group than in non-vascularised grafts. "Creeping substitution" was found in all cortical layers in vascularised grafts, whereas in conventional allografts bone resorption predominated. The experimental data suggest that in rat autogenously vascularised bone allografts show a remodelling pattern comparable with that of conventional vascularised bone autografts. The advantage of the autogenously vascularised bone allograft is that it allows transfer of a vascularised bone allograft together with its well-vascularised recipient bed without immunosuppressive treatment.
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Among the available imaging techniques such as conventional radiography, radionuclide bone scan, and computed tomography (CT), magnetic resonance imaging (MRI) has made significant contributions to the diagnosis of acute hip joint disease in adults by enabling early differentiation between such conditions as idiopathic avascular femoral head necrosis, septic coxitis, degenerative disease, and tumors. In this study we investigated the use of MRI for evaluation of patients with transient osteoporosis (TO). MRI with T1- and T2-weighted sequences in coronal, transverse, and sagittal sections was performed in 12 patients with retrospectively confirmed TO, both at the onset of the disease and later as follow-up procedure. ⋯ Characteristic symptoms of TO are hip pain and a need for protective splinting of the hip joint. Conventional radiographs show demineralization of the hip joint without joint space narrowing. Clinical, radiologic, and MRI findings normalize within 6-10 months, indicating that TO has a good prognosis with complete restoration of bone density.
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Arch Orthop Trauma Surg · Jan 1991
ReviewKnee ligament injuries combined with ipsilateral tibial and femoral diaphyseal fractures: the "floating knee".
The incidence of rupture of the knee ligaments was retrospectively studied in 47 patients with ipsilateral fractures of the femoral and tibial diaphyseal shaft. Fifteen patients proved to have an instability of the knee at the time of follow up. Disruption of the knee ligaments had not been recognised initially. ⋯ After stabilisation of both fractures in these cases, the knee ligaments had been repaired; at re-examination these patients had no complaints and their knees were perfectly stable. In view of the high incidence of missed cases, the possibility of disruption of the knee ligaments should be considered in all patients with fractures of both the femoral and tibial shaft. Meticulous examination of the knee at the time of injury is strongly advocated.