Archives of orthopaedic and trauma surgery
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Arch Orthop Trauma Surg · Jan 1990
Comparative StudyCalcitonin, estradiol, and hydroxyproline as parameters in the early diagnosis of involutional osteoporosis. The importance of the "second calcitonin phenomenon".
Bone metabolism was studied in a group of 92 subjects. A greater age-related decrease in calcitonin and estradiol concentrations exists in women than in men, though this difference was not significant; it was significant, however, when the values of the three different groups of women were compared. We present what we have called the second calcitonin phenomenon, that is, a highly significant difference in women between a second basal calcitonin level and the primary admission value. In the calcium infusion test, men considered to be osteoporotic showed a deceleration in the rapid loss of reserve calcitonin deposits.
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Arch Orthop Trauma Surg · Jan 1990
Femoral shaft perforation at arthroplasty: to treat or not to treat.
Femoral shaft perforation at total hip arthroplasty is a complication that is being noted more frequently, and it is often associated with femoral shaft fracture below the prosthesis. This study examines the anatomic and biomechanical effects of femoral shaft perforation at arthroplasty, and the effects of supporting the perforated bone with Partridge plates and bands. ⋯ Testing the bone models to failure in tensile mode showed that the perforations weakened the bone and that the Partridge plates and bands decreased the weakening effects of the perforation. The strengthening effect of the Partridge plates and bands on the bone with a perforation, allied with the presence of an internal splint in the event of a fracture through the perforation, suggests the benefit of using Partridge plates and bands if a cortical perforation is found at arthroplasty and revision is not feasible.
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Arch Orthop Trauma Surg · Jan 1990
Case ReportsA case of hip osteoarthrosis contaminated by fungi. A histological study.
A pathological study of a surgical specimen of hip osteoarthrosis presenting a superficial fungal infection (presumably Aspergillus) without any known origin is reported. Fungal penetration was mild in cartilage and fibrocartilage and more pronounced in naked cancellous bone, but it did not occur in eburnated bone or in the deep osteomedullar area. This observation indicates an unusual combination of infection and osteoarthrosis. Relationships between fungi and bone or cartilage as well as interaction between osteoarthrotic remodeling and a superimposed disease are discussed.
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Arch Orthop Trauma Surg · Jan 1990
Quantitative and functional restorations and alterations of peripheral lymphocytes in patients with autologous spleen implantation.
To reduce the risk of severe infections in splenectomized patients, new methods for splenic preservation or heterotopic autologous spleen implantation have been established. In the latter case, the immunological and functional benefits are still under discussion. In this study we compared immunological parameters in 16 splenectomized patients with and without heterotopic autologous spleen implantation with a nonsplenectomized control group. ⋯ The latter results support the findings of elevated serum IgA levels in this group. The mitogenic-induced proliferation with PHA, ConA, PWM, and OKT3 was not clearly different within the tested groups. The results may indicate a benefit of autologous spleen implantation in regard to the humoral immune response.
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Arch Orthop Trauma Surg · Jan 1990
Case ReportsHemodialysis-associated amyloidosis of bone of beta-2 microglobulin origin.
A case of hemodialysis-associated amyloidosis in a patient who had been on hemodialysis for 10 years is described. Bone lesions were found in the humeral heads, carpal bones, and femoral heads and necks. ⋯ We reconfirmed that bone lesions associated with long-term hemodialysis are manifestations of amyloidosis of beta-2 microglobulin origin. Hemodialysis-associated amyloidosis should be considered in the treatment of long-term hemodialysis patients.