Archives of orthopaedic and trauma surgery
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Arch Orthop Trauma Surg · Jul 2012
Clinical TrialDetermination of cephazolin, ceftazidime, and ceftriaxone distribution in nucleus pulposus.
The intervertebral disc is the largest avascular structure in the adult body and minimal blood flow through capillary beds only supplying the outer regions of the disc, which relies on the passive diffusion as a major factor for nutrition and uptake of molecules, including antibiotics. This study is to detect the serum and nucleus pulposus (NP) levels of cephazolin, ceftazidime, and ceftriaxone and to assess this antibiotic permeability into the intervertebral disc. ⋯ The antibiotics of cephazolin, ceftazidime, and ceftriaxone had concentration in the NP tissue, which was higher than the stated MIC. Ceftazidime had highest penetration in to NP tissue, and ceftriaxone had the lowest penetration in to NP tissue.
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Arch Orthop Trauma Surg · Jul 2012
Augmentative locking compression plate fixation for the management of long bone nonunion after intramedullary nailing.
Intramedullary nailing is widely used in the treatment of long bone fractures. But some patients suffer from nonunion after receiving intramedullary nailing. This paper investigates the methods and effects of locking compression plate (LCP) in the treatment of long bone nonunion after intramedullary nailing. ⋯ LCP can be used for the treatment of long bone nonunion after intramedullary nailing for its convenience, minimal invasion and curative effect.
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Arch Orthop Trauma Surg · Jul 2012
Small differences between anatomical and mechanical sagittal femur axes: a radiological and navigated study of 50 patients.
The purposes of the study were to define the orientation of the anatomical and mechanical axes of the femur on the lateral plane on long leg X-rays including the femoral head, and to compare these results to the intra-operative measurement of the mechanical axis by a nonimage-based navigation system. ⋯ The differences observed are small and have probably little clinical relevance. The distal cortical axis may be the best compromise. The navigation system allows measuring accurately the orientation of the distal femoral resection in the sagittal plane.
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Arch Orthop Trauma Surg · Jul 2012
Correlation of low back pain caused by lumbar spinal stenosis and depression in women: a clinical study.
Low back pain (LBP) due to spinal stenosis may be one of the most debilitating symptoms to decrease the quality of life. The cause and effect association of LBP and depression is vague. Pain may also be a somatization symptom of depression. This is more frequent in the female population. This clinical study was designed to evaluate the correlation between the level of back pain caused by lumbar spinal stenosis and depression in the female population. ⋯ Our findings indicated a relationship between lumbar spinal stenosis associated pain levels and depression. However, the cause and result relationship still needs to be established yet.
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Arch Orthop Trauma Surg · Jun 2012
Preparation of gentamicin-loaded electrospun coating on titanium implants and a study of their properties in vitro.
Implant-related infections are disastrous complications in the clinic, and there are no effective therapies. In this preliminary study, gentamicin-loaded coating on titanium implants was prepared using the electrospinning technique, and some properties of the coating titanium implants were studied. ⋯ The gentamicin-coated titanium implants, which were prepared using an electrospinning technique, present many advantages and may be considered to prevent and treat the implant-related infections.