Acta obstetricia et gynecologica Scandinavica
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Acta Obstet Gynecol Scand · Aug 2014
Clinical TrialPain evoked by distension of the uterine cervix in women with dysmenorrhea: evidence for central sensitization.
To study sensitization in women with dysmenorrhea using a standardized experimental model. Women with dysmenorrhea experience intense visceral pain during menstruation. The dysmenorrhea pain mechanisms are not known but sensitization may play a role. ⋯ Pain sensitization (temporal summation, i.e. increase in pain during prolonged stimulation, and facilitation of referred pain areas as an indicator of central nervous system changes) is present in women with dysmenorrhea. The study provided new information on a poorly understood yet widespread condition and a basis for clinical studies to develop a biomarker tests for objective assessment of dysmenorrhea.
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Acta Obstet Gynecol Scand · Aug 2014
Observational StudyImplementing a structured Enhanced Recovery After Surgery (ERAS) protocol reduces length of stay after abdominal hysterectomy.
To study the effects of introducing an Enhanced Recovery After Surgery (ERAS) protocol, modified for gynecological surgery, on length of stay and complications following abdominal hysterectomy. ⋯ Introducing the ERAS protocol for abdominal hysterectomy reduced length of stay without increasing complications or readmissions.
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Acta Obstet Gynecol Scand · Jul 2014
Observational StudyMedical abortion with mifepristone and home administration of misoprostol up to 63 days' gestation.
To evaluate the acceptability and efficacy of medical abortion at home up to 63 days' gestation without limits on travel distance to a registered institution. ⋯ In our experience, home administration of misoprostol is an effective and acceptable method for abortion up to 63 days of gestation and women should be eligible for this treatment option regardless of their travel distance from hospital.
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Acta Obstet Gynecol Scand · Jul 2014
Review Meta Analysis Comparative StudyActive management of the third stage of labor with and without controlled cord traction: a systematic review and meta-analysis of randomized controlled trials.
To determine the specific effect of controlled cord traction in the third stage of labor in the prevention of postpartum hemorrhage. ⋯ Controlled cord traction appears to reduce the risk of any postpartum hemorrhage in a general sense, as well as manual removal of the placenta and the duration of the third stage of labor. However, the reduction in the occurrence of severe postpartum hemorrhage, need for additional uterotonics and blood transfusion is not statistically significant.
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Acta Obstet Gynecol Scand · Jun 2014
ReviewA critical appraisal of the evidence for using cardiotocography plus ECG ST interval analysis for fetal surveillance in labor. Part II: the meta-analyses.
We appraised the methodology, execution and quality of the five published meta-analyses that are based on the five randomized controlled trials which compared cardiotocography (CTG)+ST analysis to cardiotocography. The meta-analyses contained errors, either created de novo in handling of original data or from a failure to recognize essential differences among the randomized controlled trials, particularly in their inclusion criteria and outcome parameters. ⋯ We believe that one randomized controlled trial excluded in two of the meta-analyses should have been included, whereas one randomized controlled trial that was included in all meta-analyses, should have been excluded. After correction of the uncovered errors and exclusion of the randomized controlled trial that we deemed inappropriate, our new meta-analysis showed that CTG+ST monitoring significantly reduces the fetal scalp blood sampling usage (risk ratio 0.64; 95% confidence interval 0.47-0.88), total operative delivery rate (0.93; 0.88-0.99) and metabolic acidosis rate (0.61; 0.41-0.91).