Acta obstetricia et gynecologica Scandinavica
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Acta Obstet Gynecol Scand · Nov 1998
Comparative StudyEffect of endothelin-1 on spontaneous contractions and effects of nimodipine and isradipine on endothelin-1-induced contractions in myometrial strips isolated from normal pregnant and preeclamptic women.
To examine the effect of endothelin-1 (ET-1) on spontaneous contractile activity and the effects of nimodipine and isradipine on ET-1-induced contractile responses in myometrial strips isolated from normal pregnant and preeclamptic women. ⋯ The increase in contractile response with ET-1 was significantly higher in myometrial strips isolated from preeclamptic women compared to those of myometrial strips isolated from normal pregnant women. These increases in contractile response are at least in part mediated by dihydropyridine-sensitive calcium channels, since they were significantly reduced in the presence of increasing concentrations of nimodipine and isradipine.
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Acta Obstet Gynecol Scand · Oct 1998
Randomized Controlled Trial Clinical TrialPain and pulmonary function following laparoscopic and abdominal hysterectomy: a randomized study.
The aim of this study was to evaluate pain and pulmonary function the first two days after abdominal and laparoscopic hysterectomy. ⋯ Laparoscopic hysterectomy results in less pain and less impairment of respiratory function compared to abdominal hysterectomy.
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Acta Obstet Gynecol Scand · Mar 1998
Comparative Study Clinical TrialCorrelation of fetal oxygen saturation to fetal heart rate patterns. Evaluation of fetal pulse oximetry with two different oxisensors.
The purpose of this study was the correlation of fetal oxygen saturation values to various fetal heart rate patterns, as well as to oxygen saturation values obtained by fetal blood analysis. These objectives need to be evaluated from the perspective that two generations of fetal oxisensors have been used. ⋯ In combination with fetal heart rate monitoring, fetal pulse oximetry promises a better differentiation between low and high risk heart rate patterns. Oxygen saturation values from intermittent fetal blood sampling reassure the clinician concerning the accuracy of this new method of intrapartum fetal surveillance and underline the increased quality of the new generation of oxisensor using light of a wavelength of 735 and 890 nm.
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Acta Obstet Gynecol Scand · Feb 1998
Randomized Controlled Trial Comparative Study Clinical TrialRandomized comparison of rectal misoprostol with Syntometrine for management of third stage of labor.
The search for an effective, easily stored, affordable uterotonic agent in preventing postpartum hemorrhage is of importance, especially in the developing world. The objective of this study was to randomly compare the effectiveness of rectal misoprostol with Syntometrine in the management of the third stage of labor. ⋯ Misoprostol rectally for management of the third stage of labor merits further investigation.