Cerebrovascular diseases
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Stroke is regarded as a possible complication of burn. Some author reported that stroke developed in 22% of burned patients. However, the true incidence and the clinical characteristics of stroke occurring after burn injury are unknown. ⋯ Stroke is a rare complication of a burn injury in the clinical setting. It develops in moderate burns (10-50% of the total body surface area) after some time. Prevention of infection/sepsis is important to alleviate the occurrence of a stroke in these patients.
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Cerebrovascular diseases · Jan 2007
Management and outcome of patients with transient ischemic attack admitted to a stroke unit.
The way in which patients with transient ischemic attack (TIA) are investigated and treated varies substantially worldwide. There are no data on the management and outcome of TIA patients admitted to a stroke unit. We assessed to what extent rapid management of TIA patients admitted to a stroke unit led to specific treatments which can prevent stroke and evaluated the early risk and predictors of stroke in these patients. ⋯ Early management of TIA in a stroke unit leads to specific treatments in a significant proportion of cases. The presence of acute lesions on DWI and the ABCD score predict the 3-month risk of stroke after TIA.
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Cerebrovascular diseases · Jan 2007
Microcirculatory dysfunction in the brain precedes changes in evoked potentials in endotoxin-induced sepsis syndrome in rats.
During sepsis progression microcirculatory dysfunction precedes macrocirculatory failure, partly explaining the occurrence of early organ dysfunction. The matter concerning microcirculatory dysfunction in the brain under septic conditions is less clear. We investigated the integrity of the activation flow coupling during sepsis progression in a rat model of septic shock. ⋯ For the first time we demonstrate microcirculatory dysfunction in the activation flow coupling of the brain. Inappropriate blood supply of neurons might explain the disturbance of neuronal function.