Cerebrovascular diseases
The most recent articles from:
Cerebrovasc. Dis.
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Cerebrovascular diseases · Jan 2006
Randomized Controlled Trial Multicenter StudyCiticoline in intracerebral haemorrhage: a double-blind, randomized, placebo-controlled, multi-centre pilot study.
In experimental models citicoline has shown beneficial effects in intracerebral haemorrhage. Citicoline is a neuroprotectant drug with some beneficial effects in human ischaemic stroke and with an excellent safety profile. We decided to carry out a pilot study to test its safety and efficacy in human intracerebral haemorrhaging. ⋯ Citicoline seems to be a safe drug in human intracerebral haemorrhage with a positive trend regarding efficacy. These data should be confirmed in a larger trial.