Journal of neuroimaging : official journal of the American Society of Neuroimaging
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To find an optimal normalizing factor for upper cervical spinal cord area (UCCA) and to establish whether, in a cross-sectional study, the normalized UCCA correlates better with the neurological disability than the absolute measurement in multiple sclerosis patients. ⋯ Our findings suggest that LECA is an optimal correction factor for UCCA and normalized UCCA is preferable to absolute measurement in cross-sectional study.
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This study aims to assess cerebral metabolites in school-aged autistic patients through proton magnetic resonance spectroscopy. ⋯ This study found a statistically significant increase in myo-inositol and choline in anterior cingulate and left striatum of autistic children compared with controls. In contrast to previous studies, NAA peak area and NAA/Cr and NAA/Cho ratios had no statistically significant decrease in any of the 4 brain regions.
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We attempted to measure DTI parameters of the brainstem pyramidal tract using two approaches, ie, simple ROI and tract-specific analyses. Results obtained for healthy subjects and ALS patients were compared. ⋯ These results suggest, compared with simple ROI analysis, that tract-specific analysis using DTI fiber-tracking is more reliable and sensitive for detecting upper motor neuron pathology in ALS.