Journal of neuroimaging : official journal of the American Society of Neuroimaging
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Comparative Study
Comparison of Intracerebral Hemorrhage Volume Calculation Methods and Their Impact on Scoring Tools.
Intracerebral hemorrhage (ICH) volumes are frequently used for prognostication and inclusion of patients in clinical trials. We sought to compare the original ABC/2 method and sABC/2, a simplified version with the planimetric method. ⋯ Simplified ABC/2 (sABC/2) method performs better than ABC/2 in calculating ICH volumes. Moreover, it is better in differentiating a volume threshold of 30 mL. These findings may have implications for outcomes prediction and clinical trials inclusion.
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Case Reports
Visualization of the Intimal Flap in Intracranial Arterial Dissection Using High-Resolution 3T MRI.
Presence of an intimal flap is a critical imaging finding in diagnosing intracranial artery dissection (ICAD). Recent reports showed that high-resolution magnetic resonance imaging (MRI) was better at identifying intimal flaps as compared with routine MRI techniques used in clinical settings. However, no current standardized sequence for high-resolution MRI without gadolinium enhancement produces images of satisfactory quality with clinically tolerable scanning times. This study evaluated a nonenhanced high-resolution fast spin echo (HR-FSE) MRI sequence for visualizing intimal flaps in patients with ICAD. ⋯ The present method of optimized HR-FSE imaging with a 3T system improved visualization of intimal flaps and should thus be considered for assessing patients with suspected ICAD that cannot be definitively diagnosed by conventional imaging modalities.
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Previous T2*-weighted magnetic resonance imaging (MRI) studies have used white matter lesion (WML) central veins to distinguish multiple sclerosis (MS) from its mimics. To be clinically applicable, the "central vein sign" needs to be detectable across different T2* sequences. Our objective was to determine if the central vein sign is reliably present in MS and absent in patients with ischemic small vessel disease (SVD) across different T2* sequences at 3T MRI. ⋯ The central vein sign can diagnose MS in the clinical setting of modern 3T scanners. However, variations in the T2* sequences need to be considered when defining a threshold for diagnosis.
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Observational Study
Transorbital Sonography and Visual Outcome for the Diagnosis and Monitoring of Optic Neuritis.
Transorbital sonography (TOS) is a promising tool to support the clinical diagnosis of optic neuritis (ON) by showing thickening of optic nerve. In this study, we aimed to define its specific role in follow-up of ON patients. ⋯ TOS is a useful tool to support diagnosis of ON. This technique seems to have less value to evaluate atrophy of the optic nerve after 12 months.
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Although high-resolution magnetic resonance imaging (HR-MRI) is considered optimal for the diagnosis of intracranial vertebral artery dissection (IVAD), it is not readily available for all patients with suspected IVAD. The purpose of our study was to determine the factor related to IVAD lesions that are not definitively diagnosed by conventional MRI. ⋯ HR-MRI may be useful for diagnosing IVAD without aneurysmal dilatation or with ipsilesional vertebral hypoplasia.