Journal of neuroimaging : official journal of the American Society of Neuroimaging
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To determine the feasibility of apparent diffusion coefficient (ADC)-based thermometry to assess intraventricular temperature in children. ⋯ ADC-based thermometry has limited application in the pediatric population mainly due to a small ventricular size.
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This study was designed to evaluate the potential of the dynamic autoregulation index (ARI) to serve as an early warning system for an imminent clinical deterioration after subarachnoid hemorrhage (SAH). ⋯ The results demonstrate the capability of the ARI to serve as a reliable early warning system after SAH. Further trials with larger study populations are needed to validate these promising preliminary data.
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Low-grade and anaplastic oligodendrogliomas are often difficult to differentiate on the basis of conventional MR imaging characteristics. Dynamic contrast-enhanced (DCE) MRI can assess tumor microvasculature and has demonstrated utility for predicting glioma grade and prognosis in primary brain tumors. The aim of our study was to evaluate the performance of plasma volume (Vp) and volume transfer coefficient (K(trans) ) derived from DCE MRI in differentiating between grade II and grade III oligodendrogliomas. ⋯ The results of our study suggest the DCE MRI parameter Vpmean can noninvasively differentiate between grade II and grade III oligodendrogliomas.
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Human entorhinal cortex (ERC) connects the temporal neocortex with hippocampus and is essential for memory retrieval and navigation. Markedly, there have been only few quantitative MRI works on the ERC geometric measurements in pediatric and adult healthy subjects across the lifespan. Here, we sought to fill this gap in knowledge by quantifying the ERC thickness in a very large cohort of subjects spanning 9 decades of life. ⋯ Our report with high spatial resolution brain MRI data from 1,660 healthy controls provided important clues about ERC thickness across lifespan. We believe that our report will pave the way for the future studies investigating distinct neural pathologies related with cognitive dysfunctions.
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Apparent diffusion coefficient (ADC) values have been shown to assist in differentiating cerebellar pilocytic astrocytomas and medulloblastomas. Previous studies have applied only ADC measurements and calculated the mean/median values. Here we investigated the value of diffusion tensor imaging (DTI) histogram characteristics of the entire tumor for differentiation of cerebellar pilocytic astrocytomas and medulloblastomas. ⋯ The 25th percentile for MD yields the best results for the presurgical differentiation between pediatric cerebellar pilocytic astrocytomas and medulloblastomas. The analysis of other DTI metrics does not provide additional diagnostic value. Our study confirms the diagnostic value of the quantitative histogram analysis of DTI data in pediatric neuro-oncology.