Journal of neuroimaging : official journal of the American Society of Neuroimaging
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Case Reports Comparative Study
7T MRI-Histologic Correlation Study of Low Specific Absorption Rate T2-Weighted GRASE Sequences in the Detection of White Matter Involvement in Multiple Sclerosis.
The high value of the specific absorption rate (SAR) of radio-frequency (RF) energy arising from the series of RF refocusing pulses in T2-weighted (T2-w) turbo spin echo (TSE) MRI hampers its clinical application at 7.0 Tesla (7T). T2-w gradient and spin echo (GRASE) uses the speed from gradient refocusing in combination with the chemical-shift/static magnetic field (B0) inhomogeneity insensitivity from spin-echo refocusing to acquire T2-w images with a limited number of refocusing RF pulses, thus reducing SAR. ⋯ T2-w GRASE images may replace T2-w TSE for clinical use. However, even at 7T, both sequences fail in detecting and characterizing MS disease beyond visible WM-Ls.
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Patients with triple-negative breast cancer (TNBC) are at increased risk of brain metastases (BMs). In this retrospective single-institutional study, we assessed the radiographic features from a cohort of breast cancer (BC) patients with confirmed BM. ⋯ Patients with BMs from TNBC have distinct MRI features helping the assessment of newly developed BM. A large confirmatory study with correlated histology in this unique patient population will be required.
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Computational models have been investigated for the analysis of the physiopathology and morphology of arteriovenous malformation (AVM) in recent years. Special emphasis has been given to image fusion in multimodal imaging and 3-dimensional rendering of the AVM, with the aim to improve the visualization of the lesion (for diagnostic purposes) and the selection of the nidus (for therapeutic aims, like the selection of the region of interest for the gamma knife radiosurgery plan). ⋯ Computational modeling in the AVM field offers promising tools of analysis and requires a strict collaboration among neurosurgeons, neuroradiologists, clinicians, computer scientists, and engineers. We present here some updated state-of-the-art exemplary cases in the field, focusing on recent neuroimaging computational modeling with clinical relevance, which might offer useful clinical tools for the management of AVMs in the future.
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Review Case Reports
Chiasmatic-hypothalamic masses in adults: a case series and review of the literature.
Chiasmatic-hypothalamic masses are commonly seen in children with neurofibromatosis type 1 and often demonstrate a benign clinical course. These masses are, however, rare in adults and require tissue sampling for diagnosis. Here, we present four cases of chiasmatic-hypothalamic masses in adults with pathologically proven diagnoses. We also provide a review of the literature and propose a limited differential in this age group.
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Review Case Reports
Convexity Subarachnoid Hemorrhage with PiB Positive Pet Scans: Clinical Features and Prognosis.
Cerebral amyloid angiopathy (CAA) has been reported to present as convexity subarachnoid hemorrhage (cSAH). Lesser known is that cSAH can herald intracerebral hemorrhage (ICH) and ischemic lesions. We present seven new cases with (11) C-Pittsburgh compound B (PiB) positive positron emission tomography (PET) scans including two with biopsy, review the literature and comment on clinical and radiological findings. ⋯ The finding of cSAH and PiB binding in our patients suggest underlying CAA. cSAH may be associated with ischemic lesion as well as future ICH occurrence.