Journal of neuroimaging : official journal of the American Society of Neuroimaging
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Flow diversion techniques are increasingly used to treat cerebral aneurysms. The optimal stent porosity to achieve aneurysm obliteration would allow clinicians to treat aneurysms more effectively. We sought to determine the optimal porosity threshold in an in vitro flow model that would lead to stagnation of flow in an aneurysm. ⋯ The current model demonstrates a method to evaluate the optimal porosity threshold to achieve thrombosis of an aneurysm as a primary modality. Moreover, a gap may occur between the stent and the aneurysm that may create unfavorable circulatory conditions by increasing flow into the aneurysm.
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Case Reports
Optic nerve sonography to monitor treatment efficacy in idiopathic intracranial hypertension: a case report.
To report values of optic nerve sheath diameter (ONSD) and optic disc elevation (ODE) obtained with optic nerve sonography (US) in the diagnosis and monitoring of treatment efficacy in an adult with idiopathic intracranial hypertension (IIH). ⋯ US of ONSD and ODE was useful to support the diagnosis of IIH and to monitor the efficacy of diet and pharmacological treatment. Further studies are required to evaluate whether this promising technique may be considered a reliable and accurate method to longitudinally evaluate patients with increased ICP secondary to IIH.
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Paradoxical embolism through extracardiac right-to-left shunts (ECRLS) may represent an under-detected stroke mechanism. Stroke patients without evidence of cardiac right-to-left shunt (RLS) on echocardiogram may benefit from transcranial Doppler with bubble study (TCD-b) to aid in recognition of stroke etiology. This study assesses the usefulness of TCD-b in the stroke evaluation. ⋯ TCD-bubble studies may prove useful in uncovering treatable causes of stroke.
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Small animal neuroimaging using magnetic resonance microscopy (MRM) has evolved significantly from understanding of imaging physics to widely use today as an important tool in computational neuroanatomy, while how to get optimal inhomogeneity correction for inhomogeneous mouse brain MRM has been given less attention. ⋯ The present study demonstrates the benefit of reducing the spline distance values to 25 and tighter mask. The finding can help researches to enhance precision in studies where mouse MRM need further registration or segmentation.
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We detail a procedure for generating a set of templates for the hippocampal region in magnetic resonance (MR) images, representative of the clinical conditions of the population under investigation. ⋯ This study describes a simple and easily reproducible procedure to generate templates for the hippocampal region. It can be generalized and applied to other brain regions, which may be relevant for neuroimaging studies.